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1.
Biological and methodological complexities of beta-amyloid peptide: Implications for Alzheimer's disease research.
J Neurochem
; 160(4): 434-453, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34767256
2.
Persistent DNA damage alters the neuronal transcriptome suggesting cell cycle dysregulation and altered mitochondrial function.
Eur J Neurosci
; 54(9): 6987-7005, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34536321
3.
Transcriptomic Analysis of Human Astrocytes In Vitro Reveals Hypoxia-Induced Mitochondrial Dysfunction, Modulation of Metabolism, and Dysregulation of the Immune Response.
Int J Mol Sci
; 21(21)2020 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33126586
4.
NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.
Int J Mol Sci
; 21(1)2020 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31947996
5.
Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain.
Glia
; 66(11): 2316-2323, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30098078
6.
Proteomic and cellular localisation studies suggest non-tight junction cytoplasmic and nuclear roles for occludin in astrocytes.
Eur J Neurosci
; 47(12): 1444-1456, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29738614
7.
Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology.
Neuropathol Appl Neurobiol
; 42(2): 167-79, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26095650
8.
Astrocytes and neuroinflammation in Alzheimer's disease.
Biochem Soc Trans
; 42(5): 1321-5, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25233410
9.
DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort.
Neuropathol Appl Neurobiol
; 40(7): 802-14, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24861546
10.
Advanced Glycation End Product Formation in Human Cerebral Cortex Increases With Alzheimer-Type Neuropathologic Changes but Is Not Independently Associated With Dementia in a Population-Derived Aging Brain Cohort.
J Neuropathol Exp Neurol
; 79(9): 950-958, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32766675
11.
Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons.
Neuroscience
; 390: 46-59, 2018 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30056117
12.
A reduced astrocyte response to ß-amyloid plaques in the ageing brain associates with cognitive impairment.
PLoS One
; 10(2): e0118463, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25707004
13.
The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain.
Neurosci Lett
; 609: 11-7, 2015 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26455863
14.
Insulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors.
Mol Brain
; 8: 51, 2015 Aug 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-26297026
15.
Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aß in Alzheimer's disease.
Aging Cell
; 13(1): 49-59, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23919677
16.
Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype.
Neurobiol Aging
; 32(10): 1795-807, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21705112
17.
Anti-inflammatory impact of minocycline in a mouse model of tauopathy.
Front Psychiatry
; 1: 136, 2010.
Artículo
en Inglés
| MEDLINE | ID: mdl-21423446
18.
Minocycline as a potential therapeutic agent in neurodegenerative disorders characterised by protein misfolding.
Prion
; 3(2): 78-83, 2009.
Artículo
en Inglés
| MEDLINE | ID: mdl-19458490
19.
Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases.
J Biol Chem
; 283(26): 18177-86, 2008 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18467332
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