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1.
Peptide antagonists of the calcitonin gene-related peptide (CGRP) receptor with improved pharmacokinetics and pharmacodynamics.
Biopolymers
; 100(4): 422-30, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23868210
2.
An acyl-ghrelin-specific neutralizing antibody inhibits the acute ghrelin-mediated orexigenic effects in mice.
Mol Pharmacol
; 75(4): 901-7, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19129426
3.
Discovery of the Migraine Prevention Therapeutic Aimovig (Erenumab), the First FDA-Approved Antibody against a G-Protein-Coupled Receptor.
ACS Pharmacol Transl Sci
; 2(6): 485-490, 2019 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32259079
4.
Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity.
J Med Chem
; 51(9): 2758-65, 2008 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-18412318
5.
Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3.
J Med Chem
; 58(17): 6784-802, 2015 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26288216
6.
Interactions between PEG and type I soluble tumor necrosis factor receptor: modulation by pH and by PEGylation at the N terminus.
Protein Sci
; 11(7): 1825-33, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12070334
7.
Mono-N-terminal poly(ethylene glycol)-protein conjugates.
Adv Drug Deliv Rev
; 54(4): 477-85, 2002 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-12052710
8.
Peptibodies: A flexible alternative format to antibodies.
MAbs
; 4(5): 586-91, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22820181
9.
Ligand-binding mass spectrometry to study biotransformation of fusion protein drugs and guide immunoassay development: strategic approach and application to peptibodies targeting the thrombopoietin receptor.
AAPS J
; 12(4): 576-85, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20625864
10.
Investigation of the effects of altered receptor binding activity on the clearance of erythropoiesis-stimulating proteins: Nonerythropoietin receptor-mediated pathways may play a major role.
J Pharm Sci
; 98(6): 2198-211, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-18837016
11.
Identification of potent, selective, and metabolically stable peptide antagonists to the calcitonin gene-related peptide (CGRP) receptor.
J Med Chem
; 51(24): 7889-97, 2008 Dec 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-19053766
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