Detalles de la búsqueda
1.
JNJ-10450232 (NTM-006), A novel non-opioid with structural similarities to acetaminophen, produces relatively long-lasting analgesia after a single dose in patients undergoing 3rd molar extraction.
Regul Toxicol Pharmacol
; : 105480, 2023 Aug 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37625518
2.
Metabolism and disposition of JNJ-10450232 (NTM-006) in rats, dogs, monkeys and humans.
Regul Toxicol Pharmacol
; : 105379, 2023 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36931586
3.
First-in-human study to evaluate the safety, tolerability and pharmacokinetics of a novel analgesic and antipyretic drug with structural similarity to acetaminophen.
Regul Toxicol Pharmacol
; 134: 105236, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-35934140
4.
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen.
Regul Toxicol Pharmacol
; 118: 104788, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33153971
5.
A critical review of the acetaminophen preclinical carcinogenicity and tumor promotion data and their implications for its carcinogenic hazard potential.
Regul Toxicol Pharmacol
; 118: 104801, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33039518
6.
An open-label, randomized, four-treatment crossover study evaluating the effects of salt form, acetaminophen, and food on the pharmacokinetics of phenylephrine.
Regul Toxicol Pharmacol
; 95: 333-338, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29635061
7.
Analgesic onset and efficacy of a fast-acting formulation of acetaminophen in a postoperative dental impaction pain model.
Curr Med Res Opin
; 40(2): 267-277, 2024 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38124555
8.
Single-Dose Pharmacokinetics and Metabolism of the Oral Decongestant Phenylephrine HCl in Children and Adolescents.
Pulm Ther
; 9(1): 139-150, 2023 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-36480111
9.
Objective and self-reported evidence of dextromethorphan antitussive efficacy in children, aged 6-11 years, with acute cough due to the common cold.
Pediatr Pulmonol
; 58(8): 2229-2239, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37232330
10.
Testing and Psychometric Validation of a Pediatric Instrument to Self-Assess Symptoms of the Common Cold.
Patient
; 14(1): 101-117, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33174079
11.
Development and Content Validity Testing of Patient-Reported Outcome Items for Children to Self-Assess Symptoms of the Common Cold.
Patient
; 13(2): 235-250, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31858430
12.
A randomized, placebo-controlled, exploratory trial of Ibuprofen and pseudoephedrine in the treatment of primary nocturnal enuresis in children.
Clin Pediatr (Phila)
; 48(4): 410-9, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19258524
13.
A Multicenter, Randomized, Placebo-Controlled Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold.
J Clin Pharmacol
; 59(12): 1573-1583, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31274197
14.
Single-Dose Pharmacokinetic Study of Diphenhydramine HCl in Children and Adolescents.
Clin Pharmacol Drug Dev
; 7(4): 400-407, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28967696
15.
Aminotransferase activities in healthy subjects receiving three-day dosing of 4, 6, or 8 grams per day of acetaminophen.
Clin Toxicol (Phila)
; 45(1): 36-44, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17357380
16.
Comparison of the Efficacy and Safety of 2 Acetaminophen Dosing Regimens in Febrile Infants and Children: A Report on 3 Legacy Studies.
J Pediatr Pharmacol Ther
; 22(1): 22-32, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28337078
17.
Pharmacokinetics, safety, and cardiovascular tolerability of phenylephrine HCl 10, 20, and 30 mg after a single oral administration in healthy volunteers.
Clin Drug Investig
; 35(9): 547-58, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26267590
18.
Multiple-dose pharmacokinetics and safety of an ibuprofen-pseudoephedrine cold suspension in children.
Clin Pediatr (Phila)
; 49(7): 678-85, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-20356918
19.
Reply to comments by Gonzalez et al. on the CONCERTA, Adderall XR Food Evaluation (CAFE) study.
Curr Med Res Opin
; 19(1): 64-5, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-12661783
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