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1.
Straightforward Access to a New Class of Dual DYRK1A/CLK1 Inhibitors Possessing a Simple Dihydroquinoline Core.
Molecules
; 28(1)2022 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36615235
2.
Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy.
Molecules
; 24(7)2019 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30939771
3.
Access to Highly Enantioenriched Donepezil-like 1,4-Dihydropyridines as Promising Anti-Alzheimer Prodrug Candidates via Enantioselective Tsuji Allylation and Organocatalytic Aza-Ene-Type Domino Reactions.
J Org Chem
; 83(17): 10231-10240, 2018 09 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30004228
4.
Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate.
J Org Chem
; 80(13): 6537-44, 2015 Jul 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26098725
5.
Design, synthesis and preliminary biological evaluation of rivastigmine-INDY hybrids as multitarget ligands against Alzheimer's disease by targeting butyrylcholinesterase and DYRK1A/CLK1 kinases.
RSC Med Chem
; 15(3): 963-980, 2024 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-38516603
6.
Concise synthesis of an enantiopure bicyclic pyrazinone as constrained peptidomimetic building block.
Org Biomol Chem
; 10(10): 2003-7, 2012 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-22302309
7.
Highly regio- and diastereoselective anionic [3 + 2] cycloaddition under phase transfer catalytic conditions.
J Org Chem
; 76(10): 4194-9, 2011 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-21488679
8.
Organocatalyzed enantioselective protonation of silyl enol ethers: scope, limitations, and application to the preparation of enantioenriched homoisoflavones.
J Org Chem
; 75(22): 7704-16, 2010 Nov 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-20958068
9.
Synthesis of pyrazolines by a site isolated resin-bound reagents methodology.
Org Biomol Chem
; 8(14): 3287-93, 2010 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-20502817
10.
Product-catalyzed addition of alkyl nitriles to unactivated imines promoted by sodium aryloxide/ethyl(trimethylsilyl)acetate (ETSA) combination.
J Org Chem
; 74(9): 3516-9, 2009 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19358522
11.
Novel donepezil-like N-benzylpyridinium salt derivatives as AChE inhibitors and their corresponding dihydropyridine "bio-oxidizable" prodrugs: Synthesis, biological evaluation and structure-activity relationship.
Eur J Med Chem
; 145: 165-190, 2018 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29324339
12.
Rational design of carbamate-based dual binding site and central AChE inhibitors by a "biooxidisable" prodrug approach: Synthesis, in vitro evaluation and docking studies.
Eur J Med Chem
; 155: 171-182, 2018 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29886321
13.
Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a "Bio-Oxidizable" Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation.
J Med Chem
; 60(13): 5909-5926, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28613859
14.
Dihydroquinoline Carbamate Derivatives as "Bio-oxidizable" Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation.
ACS Chem Neurosci
; 6(5): 737-44, 2015 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25695305
15.
Determination of glycols in biological specimens by gas chromatography-mass spectrometry.
J Anal Toxicol
; 26(5): 280-5, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-12166815
16.
Palladium catalyzed one-pot sequential Suzuki cross-coupling-direct C-H functionalization of imidazo[1,2-a]pyrazines.
Org Lett
; 14(23): 6012-5, 2012 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-23151283
17.
Scaffold hopping strategy toward original pyrazolines as selective CB2 receptor ligands.
Eur J Med Chem
; 58: 396-404, 2012 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-23151320
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