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1.
Pulmonary toxicity in rats following inhalation exposure to poorly soluble particles: The issue of impaired clearance and the relevance for human health hazard and risk assessment.
Regul Toxicol Pharmacol
; 109: 104498, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31604110
2.
Critical elements for human health risk assessment of less than lifetime exposures.
Regul Toxicol Pharmacol
; 81: 362-371, 2016 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-27664324
3.
Response to letter to editor "Pulmonary toxicity in rats following inhalation exposure to poorly soluble particles of low toxicity: Testing at excessive concentrations overwhelming lung clearance"?
Regul Toxicol Pharmacol
; 112: 104593, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32007437
4.
Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats.
Part Fibre Toxicol
; 11: 30, 2014 Jul 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-24993397
5.
Human risk assessment of dermal and inhalation exposures to chemicals assessed by route-to-route extrapolation: the necessity of kinetic data.
Regul Toxicol Pharmacol
; 70(1): 54-64, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24912090
6.
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA--EURL ECVAM ADME workshop.
Regul Toxicol Pharmacol
; 68(1): 119-39, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24287156
7.
The importance of variations in in vitro dosimetry to support risk assessment of inhaled toxicants.
ALTEX
; 41(1): 91-103, 2024 01 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37843016
8.
Proper knowledge on toxicokinetics improves human hazard testing and subsequent health risk characterisation. A case study approach.
Regul Toxicol Pharmacol
; 67(3): 325-34, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24051162
9.
Towards an animal-free human health assessment: starting from the current regulatory needs.
ALTEX
; 37(3): 395-408, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32113186
10.
Inhibition of LPS-induced pulmonary inflammation by specific flavonoids.
Biochem Biophys Res Commun
; 382(3): 598-603, 2009 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-19292976
11.
Poly (ADP-ribose) polymerase-1-inhibiting flavonoids attenuate cytokine release in blood from male patients with chronic obstructive pulmonary disease or type 2 diabetes.
J Nutr
; 139(5): 952-7, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19321592
12.
The importance of inclusion of kinetic information in the extrapolation of high-to-low concentrations for human limit setting.
Toxicol Lett
; 282: 81-92, 2018 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29030269
13.
Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression.
Eur J Pharmacol
; 573(1-3): 241-8, 2007 Nov 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-17643414
14.
Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations.
Biochem Pharmacol
; 72(7): 902-10, 2006 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-16870158
15.
Risk assessment of titanium dioxide nanoparticles via oral exposure, including toxicokinetic considerations.
Nanotoxicology
; 10(10): 1515-1525, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27680428
16.
Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells.
Biochem Pharmacol
; 67(8): 1607-17, 2004 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15041478
17.
Tissue distribution of inhaled micro- and nano-sized cerium oxide particles in rats: results from a 28-day exposure study.
Toxicol Sci
; 127(2): 463-73, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22430073
18.
Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine.
Eur J Pharmacol
; 629(1-3): 132-9, 2010 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-19962977
19.
Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells.
J Nutr
; 137(10): 2190-5, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17884996
20.
Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells.
Biochem Biophys Res Commun
; 338(4): 1805-10, 2005 Dec 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-16289039
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