Detalles de la búsqueda
1.
Vesatolimod, a Toll-like Receptor 7 Agonist, Induces Immune Activation in Virally Suppressed Adults Living With Human Immunodeficiency Virus-1.
Clin Infect Dis
; 72(11): e815-e824, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33043969
2.
Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies.
Anal Biochem
; 617: 114118, 2021 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33508271
3.
A Phase 2b, Randomized, Double-blind, Placebo-Controlled Multicenter Study Evaluating Antiviral Effects, Pharmacokinetics, Safety, and Tolerability of Presatovir in Hematopoietic Cell Transplant Recipients with Respiratory Syncytial Virus Infection of the Lower Respiratory Tract.
Clin Infect Dis
; 71(11): 2787-2795, 2020 12 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-31915807
4.
A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial of Presatovir for the Treatment of Respiratory Syncytial Virus Upper Respiratory Tract Infection in Hematopoietic-Cell Transplant Recipients.
Clin Infect Dis
; 71(11): 2777-2786, 2020 12 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-31793991
5.
An LC-MS/MS method for determination of tenofovir (TFV) in human plasma following tenofovir alafenamide (TAF) administration: Development, validation, cross-validation, and use of formic acid as plasma TFV stabilizer.
Anal Biochem
; 593: 113611, 2020 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32035040
6.
Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1.
N Engl J Med
; 373(8): 705-13, 2015 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26196665
7.
The safety and effectiveness of ledipasvir-sofosbuvir in adolescents 12-17 years old with hepatitis C virus genotype 1 infection.
Hepatology
; 66(2): 371-378, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27997679
8.
The Drug-Drug Interaction Potential of Antiviral Agents for the Treatment of Chronic Hepatitis C Infection.
Drug Metab Dispos
; 46(8): 1212-1225, 2018 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-29695614
9.
Sofosbuvir plus ribavirin with or without peginterferon for the treatment of hepatitis C virus: Results from a phase 3b study in China.
J Gastroenterol Hepatol
; 33(6): 1168-1176, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29380415
10.
Preclinical Pharmacokinetics and First-in-Human Pharmacokinetics, Safety, and Tolerability of Velpatasvir, a Pangenotypic Hepatitis C Virus NS5A Inhibitor, in Healthy Subjects.
Antimicrob Agents Chemother
; 61(5)2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28193657
11.
A randomized controlled trial of presatovir for respiratory syncytial virus after lung transplant.
J Heart Lung Transplant
; 42(7): 908-916, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36964084
12.
Physiologically-Based Pharmacokinetic Modeling of Remdesivir and Its Metabolites to Support Dose Selection for the Treatment of Pediatric Patients With COVID-19.
Clin Pharmacol Ther
; 109(4): 1116-1124, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33501997
13.
Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor.
Clin Pharmacokinet
; 60(5): 569-583, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33782830
14.
Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda.
Antimicrob Agents Chemother
; 54(1): 52-9, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19841149
15.
Safety, Tolerability, and Pharmacokinetics of Remdesivir, An Antiviral for Treatment of COVID-19, in Healthy Subjects.
Clin Transl Sci
; 13(5): 896-906, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32589775
16.
Safety, pharmacokinetics and pharmacodynamics of selgantolimod, an oral Toll-like receptor 8 agonist: a Phase Ia study in healthy subjects.
Antivir Ther
; 25(3): 171-180, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32667286
17.
Clinical pharmacology of artemisinin-based combination therapies.
Clin Pharmacokinet
; 47(2): 91-102, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18193915
18.
Drug-Drug Interaction Profile of the Fixed-Dose Combination Tablet Regimen Ledipasvir/Sofosbuvir.
Clin Pharmacokinet
; 57(11): 1369-1383, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29644537
19.
A Thorough QT Study to Evaluate the Effects of Supratherapeutic Doses of Ledipasvir on the QTc Interval in Healthy Subjects.
Clin Pharmacol Drug Dev
; 7(6): 641-651, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29058821
20.
Phase 1 First-in-Human, Single- and Multiple-Ascending Dose, and Food Effect Studies to Assess the Safety, Tolerability, and Pharmacokinetics of Presatovir for the Treatment of Respiratory Syncytial Virus Infection.
J Clin Pharmacol
; 58(8): 1025-1034, 2018 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-29663420