Detalles de la búsqueda
1.
Clinical application of whole-exome sequencing across clinical indications.
Genet Med
; 18(7): 696-704, 2016 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-26633542
2.
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
Genet Med
; 18(8): 823-32, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-26681312
3.
Assessing copy number from exome sequencing and exome array CGH based on CNV spectrum in a large clinical cohort.
Genet Med
; 17(8): 623-9, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25356966
4.
Further supporting evidence for the SATB2-associated syndrome found through whole exome sequencing.
Am J Med Genet A
; 167A(5): 1026-32, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25885067
5.
The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression.
FASEB J
; 27(6): 2145-55, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23430973
6.
The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia.
Blood
; 117(2): 563-74, 2011 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-20940416
7.
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development.
Proc Natl Acad Sci U S A
; 105(5): 1448-53, 2008 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-18245389
8.
The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei.
Mol Microbiol
; 73(5): 826-43, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19555461
9.
The Kennedy pathway--De novo synthesis of phosphatidylethanolamine and phosphatidylcholine.
IUBMB Life
; 62(6): 414-28, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20503434
10.
Lipidomic analysis of bloodstream and procyclic form Trypanosoma brucei.
Parasitology
; 137(9): 1357-92, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20602846
11.
Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia.
Haematologica
; 94(9): 1266-73, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19734418
12.
Biochemical characterization of the initial steps of the Kennedy pathway in Trypanosoma brucei: the ethanolamine and choline kinases.
Biochem J
; 415(1): 135-44, 2008 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18489261
13.
A clinical survey of mosaic single nucleotide variants in disease-causing genes detected by exome sequencing.
Genome Med
; 11(1): 48, 2019 07 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-31349857
14.
Reversal of the glycolytic phenotype of primary effusion lymphoma cells by combined targeting of cellular metabolism and PI3K/Akt/ mTOR signaling.
Oncotarget
; 7(5): 5521-37, 2016 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26575168
15.
ON 01910.Na is selectively cytotoxic for chronic lymphocytic leukemia cells through a dual mechanism of action involving PI3K/AKT inhibition and induction of oxidative stress.
Clin Cancer Res
; 18(7): 1979-91, 2012 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22351695
16.
Structure-based selectivity optimization of piperidine-pteridine derivatives as potent Leishmania pteridine reductase inhibitors.
J Med Chem
; 55(19): 8318-29, 2012 Oct 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-22946585
17.
Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1.
Leuk Lymphoma
; 52(9): 1758-69, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21649540
18.
Suppressive effect of human herpesvirus-8/Kaposi sarcoma-associated herpesvirus on in vitro colony formation of hematopoietic progenitor cells.
Leuk Res
; 29(8): 951-3, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15978946
19.
Role of perforin-mediated cell apoptosis in murine models of infusion-induced bone marrow failure.
Exp Hematol
; 37(4): 477-86, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19216020
20.
Noxa mediates bortezomib induced apoptosis in both sensitive and intrinsically resistant mantle cell lymphoma cells and this effect is independent of constitutive activity of the AKT and NF-kappaB pathways.
Leuk Lymphoma
; 49(4): 798-808, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18398749