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1.
Drug clearance by aldehyde oxidase: can we avoid clinical failure?
Xenobiotica
; 52(8): 890-903, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-36170034
2.
Use of a physiologically based pharmacokinetic-pharmacodynamic model for initial dose prediction and escalation during a paediatric clinical trial.
Br J Clin Pharmacol
; 87(3): 1378-1389, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32822519
3.
Application of Azamulin to Determine the Contribution of CYP3A4/5 to Drug Metabolic Clearance Using Human Hepatocytes.
Drug Metab Dispos
; 48(9): 778-787, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32532738
4.
(-)-N-3-Benzylphenobarbital Is Superior to Omeprazole and (+)-N-3-Benzylnirvanol as a CYP2C19 Inhibitor in Suspended Human Hepatocytes.
Drug Metab Dispos
; 48(11): 1121-1128, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32839278
5.
Impact of In Vitro Passive Permeability in a P-gp-transfected LLC-PK1 Model on the Prediction of the Rat and Human Unbound Brain-to-Plasma Concentration Ratio.
Pharm Res
; 37(9): 175, 2020 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32856111
6.
Setup of human liver-chips integrating 3D models, microwells and a standardized microfluidic platform as proof-of-concept study to support drug evaluation.
Biomater Biosyst
; 7: 100054, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-36824483
7.
Monitoring of a progressive functional dopaminergic deficit in the A53T-AAV synuclein rats by combining 6-[18F]fluoro-L-m-tyrosine imaging and motor performances analysis.
Neurobiol Aging
; 107: 142-152, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34433125
8.
Role of P-glycoprotein in the brain disposition of seletalisib: Evaluation of the potential for drug-drug interactions.
Eur J Pharm Sci
; 142: 105122, 2020 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31678424
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