Detalles de la búsqueda
1.
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study.
Molecules
; 27(12)2022 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35744791
2.
Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein.
Molecules
; 27(23)2022 Dec 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36500607
3.
Chemical Modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazole-2-one Scaffold as a Novel NLRP3 Inhibitor.
Molecules
; 26(13)2021 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-34209843
4.
Development of covalent NLRP3 inflammasome inhibitors: Chemistry and biological activity.
Arch Biochem Biophys
; 670: 116-139, 2019 07 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-30448387
5.
Chemical modifications of Tonda Gentile Trilobata hazelnut and derived processing products under different infrared and hot-air roasting conditions: a combined analytical study.
J Sci Food Agric
; 98(12): 4561-4569, 2018 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-29505171
6.
The effect of hazelnut roasted skin from different cultivars on the quality attributes, polyphenol content and texture of fresh egg pasta.
J Sci Food Agric
; 95(8): 1678-88, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25123494
7.
Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs.
Bioorg Med Chem
; 20(2): 841-50, 2012 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22222158
8.
Multitarget Antioxidant NO-Donor Organic Nitrates: A Novel Approach to Overcome Nitrates Tolerance, an Ex Vivo Study.
Antioxidants (Basel)
; 11(1)2022 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35052670
9.
Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia.
Cell Death Dis
; 13(6): 576, 2022 06 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35773274
10.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety.
J Med Chem
; 65(19): 12701-12724, 2022 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36162075
11.
Effective deploying of a novel DHODH inhibitor against herpes simplex type 1 and type 2 replication.
Antiviral Res
; 189: 105057, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33716051
12.
The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia.
Cancers (Basel)
; 13(5)2021 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33670894
13.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety.
J Med Chem
; 64(9): 5404-5428, 2021 05 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33844533
14.
Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution.
Pharmaceutics
; 11(2)2019 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30717376
15.
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.
Eur J Med Chem
; 163: 266-280, 2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30529545
16.
Novel antioxidant agents deriving from molecular combination of Vitamin C and NO-donor moieties.
Bioorg Med Chem
; 16(9): 5199-206, 2008 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18359636
17.
Use of human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors in Autoimmune Diseases and New Perspectives in Cancer Therapy.
Recent Pat Anticancer Drug Discov
; 13(1): 86-105, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29119937
18.
A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation.
Front Pharmacol
; 9: 1405, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30559669
19.
α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis.
Cell Death Dis
; 9(7): 756, 2018 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29988033
20.
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors.
J Med Chem
; 61(14): 6034-6055, 2018 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-29939742