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1.
Extensive splicing of transcripts encoding the bile acid-conjugating enzyme UGT2B4 modulates glucuronidation.
Pharmacogenet Genomics
; 20(3): 195-210, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20139797
2.
Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.
Drug Metab Dispos
; 38(10): 1785-9, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20610558
3.
Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.
Hum Mutat
; 30(4): 677-87, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19204906
4.
UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans.
Mutat Res
; 644(1-2): 56-63, 2008 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-18675828
5.
Faster progression from MCI to probable AD for carriers of a single-nucleotide polymorphism associated with type 2 diabetes.
Neurobiol Aging
; 64: 157.e11-157.e17, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29338921
6.
Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.
Pharmacogenetics
; 14(8): 501-15, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15284532
7.
SRD5A polymorphisms and biochemical failure after radical prostatectomy.
Eur Urol
; 60(6): 1226-34, 2011 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-21715084
8.
Regulation of the UGT1A1 bilirubin-conjugating pathway: role of a new splicing event at the UGT1A locus.
Hepatology
; 45(1): 128-38, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17187418
9.
Genetic diversity at the UGT1 locus is amplified by a novel 3' alternative splicing mechanism leading to nine additional UGT1A proteins that act as regulators of glucuronidation activity.
Pharmacogenet Genomics
; 17(12): 1077-89, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18004212
10.
The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.
Drug Metab Dispos
; 34(7): 1220-8, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16595709
11.
UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver.
Hepatology
; 42(2): 448-57, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15986396
12.
Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha.
Mol Pharmacol
; 67(1): 241-9, 2005 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-15470081
13.
Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.
J Pharmacol Exp Ther
; 307(1): 117-28, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-12944498
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