Detalles de la búsqueda
1.
Pharmacokinetics of long-acting lenacapavir in participants with hepatic or renal impairment.
Antimicrob Agents Chemother
; 68(4): e0134423, 2024 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38456707
2.
Personalized Cancer Vaccines: Clinical Landscape, Challenges, and Opportunities.
Mol Ther
; 29(2): 555-570, 2021 02 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33038322
3.
Confounding factors in exposure-response analyses and mitigation strategies for monoclonal antibodies in oncology.
Br J Clin Pharmacol
; 87(6): 2493-2501, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33217012
4.
Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma.
Pharm Res
; 37(12): 252, 2020 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33258982
5.
Application of a Novel 'Make and Test in Parallel' Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects.
Pharm Res
; 35(12): 233, 2018 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30324422
6.
Correction to: Application of a Novel 'Make and Test in Parallel' Strategy to Investigate the Effect of Formulation on the Pharmacokinetics of GDC-0810 in Healthy Subjects.
Pharm Res
; 35(12): 244, 2018 10 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30367284
7.
A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory.
Pharm Res
; 35(6): 122, 2018 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29675616
8.
Population pharmacokinetics and exposure-response of trastuzumab emtansine in advanced breast cancer previously treated with ≥2 HER2-targeted regimens.
Br J Clin Pharmacol
; 83(12): 2767-2777, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28733983
9.
Platform model describing pharmacokinetic properties of vc-MMAE antibody-drug conjugates.
J Pharmacokinet Pharmacodyn
; 44(6): 537-548, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28918591
10.
Semi-mechanistic Multiple-Analyte Pharmacokinetic Model for an Antibody-Drug-Conjugate in Cynomolgus Monkeys.
Pharm Res
; 32(6): 1907-19, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25467958
11.
Population Pharmacokinetics of Sacituzumab Govitecan in Patients with Metastatic Triple-Negative Breast Cancer and Other Solid Tumors.
Clin Pharmacokinet
; 63(5): 669-681, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38578394
12.
A study of the pharmacokinetics, safety, and efficacy of bictegravir/emtricitabine/tenofovir alafenamide in virologically suppressed pregnant women with HIV.
AIDS
; 38(1): F1-F9, 2024 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37939141
13.
Preclinical safety profile of trastuzumab emtansine (T-DM1): mechanism of action of its cytotoxic component retained with improved tolerability.
Toxicol Appl Pharmacol
; 273(2): 298-313, 2013 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24035823
14.
Optimizing outcomes and managing adverse events in locally advanced or metastatic urothelial cancer: a clinical pharmacology perspective.
Expert Rev Clin Pharmacol
; 16(6): 533-548, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37282597
15.
Pharmacokinetics, safety, and tolerability of inhaled remdesivir in healthy participants.
Clin Transl Sci
; 16(11): 2276-2288, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37688349
16.
A phase 1 study of weekly dosing of trastuzumab emtansine (T-DM1) in patients with advanced human epidermal growth factor 2-positive breast cancer.
Cancer
; 118(23): 5733-40, 2012 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22648179
17.
Evolution of preclinical characterization and insights into clinical pharmacology of checkpoint inhibitors approved for cancer immunotherapy.
Clin Transl Sci
; 15(8): 1818-1837, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35588531
18.
Integrating real-world data to accelerate and guide drug development: A clinical pharmacology perspective.
Clin Transl Sci
; 15(10): 2293-2302, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35912537
19.
Evaluation of atezolizumab immunogenicity: Clinical pharmacology (part 1).
Clin Transl Sci
; 15(1): 130-140, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34432389
20.
Real-world data prognostic model of overall survival in patients with advanced NSCLC receiving anti-PD-1/PD-L1 immune checkpoint inhibitors as second-line monotherapy.
Cancer Rep (Hoboken)
; 5(10): e1578, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35075804