Detalles de la búsqueda
1.
Structure-guided identification of a selective sulfonamide-based inhibitor targeting the human carbonic anhydrase VA isoform.
Arch Pharm (Weinheim)
; 356(1): e2200383, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36250310
2.
Leveraging the 3-Chloro-4-fluorophenyl Motif to Identify Inhibitors of Tyrosinase from Agaricus bisporus.
Int J Mol Sci
; 24(9)2023 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37175649
3.
Synthesis and biological evaluation of sulfonamide-based compounds as inhibitors of carbonic anhydrase from Vibrio cholerae.
Arch Pharm (Weinheim)
; 355(10): e2200070, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-35739618
4.
Ligand-Based Discovery of a Small Molecule as Inhibitor of α-Synuclein Amyloid Formation.
Int J Mol Sci
; 23(23)2022 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36499173
5.
Taking advantage of lithium monohalocarbenoid intrinsic α-elimination in 2-MeTHF: controlled epoxide ring-opening en route to halohydrins.
Org Biomol Chem
; 19(9): 2038-2043, 2021 03 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33599644
6.
Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VII.
Bioorg Med Chem
; 44: 116279, 2021 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34216985
7.
Exploring Molecular Contacts of MUC1 at CIN85 Binding Interface to Address Future Drug Design Efforts.
Int J Mol Sci
; 22(4)2021 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33672244
8.
In Silico Identification of Potential Druggable Binding Sites on CIN85 SH3 Domain.
Int J Mol Sci
; 22(2)2021 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33430321
9.
In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules.
Molecules
; 26(4)2021 Feb 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-33669763
10.
Inhibition of HIV-1 RT activity by a new series of 3-(1,3,4-thiadiazol-2-yl)thiazolidin-4-one derivatives.
Bioorg Med Chem
; 28(8): 115431, 2020 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32197813
11.
Discovery of a new potent inhibitor of mushroom tyrosinase (Agaricus bisporus) containing 4-(4-hydroxyphenyl)piperazin-1-yl moiety.
Bioorg Med Chem
; 28(11): 115497, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32312487
12.
Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson's disease.
J Enzyme Inhib Med Chem
; 35(1): 1727-1735, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32924648
13.
Synthesis, computational studies and assessment of in vitro inhibitory activity of umbelliferon-based compounds against tumour-associated carbonic anhydrase isoforms IX and XII.
J Enzyme Inhib Med Chem
; 35(1): 1442-1449, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32614678
14.
Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives.
J Enzyme Inhib Med Chem
; 34(1): 1186-1192, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31282228
15.
The link between the AMPK/SIRT1 axis and a flavonoid-rich extract of Citrus bergamia juice: A cell-free, in silico, and in vitro study.
Phytother Res
; 33(7): 1805-1814, 2019 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-31094018
16.
Identification of influenza PA-Nter endonuclease inhibitors using pharmacophore- and docking-based virtual screening.
Bioorg Med Chem
; 26(15): 4544-4550, 2018 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30082105
17.
Structure-guided design of new indoles as negative allosteric modulators (NAMs) of N-methyl-D-aspartate receptor (NMDAR) containing GluN2B subunit.
Bioorg Med Chem
; 24(7): 1513-9, 2016 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26912202
18.
Searching for indole derivatives as potential mushroom tyrosinase inhibitors.
J Enzyme Inhib Med Chem
; 31(3): 398-403, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-25826148
19.
Optimization of rhodanine scaffold for the development of protein-protein interaction inhibitors.
Bioorg Med Chem
; 23(13): 3208-14, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25999203
20.
A new potential approach to block HIV-1 replication via protein-protein interaction and strand-transfer inhibition.
Bioorg Med Chem
; 22(7): 2269-79, 2014 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24618511