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1.
Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite.
Drug Metab Dispos
; 48(10): 873-885, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32665418
2.
Metabolism and Disposition of Siponimod, a Novel Selective S1P1/S1P5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism.
Drug Metab Dispos
; 46(7): 1001-1013, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29735753
3.
Absorption, Distribution, Metabolism, and Excretion of the Oral Prostaglandin D2 Receptor 2 Antagonist Fevipiprant (QAW039) in Healthy Volunteers and In Vitro.
Drug Metab Dispos
; 45(7): 817-825, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28442499
4.
Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease.
J Med Chem
; 64(11): 7241-7260, 2021 06 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34028270
5.
Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state.
Drug Metab Dispos
; 38(5): 808-16, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20097723
6.
An integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data.
Pharmacol Res Perspect
; 8(3): e00599, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32524755
7.
Absorption, distribution, metabolism, and excretion of [(14)C]BYL719 (alpelisib) in healthy male volunteers.
Cancer Chemother Pharmacol
; 76(4): 751-60, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26254025
8.
Metabolism and disposition of the oral absorption enhancer 14C-radiolabeled 8-(N-2-hydroxy-5-chlorobenzoyl)-amino-caprylic acid (5-CNAC) in healthy postmenopausal women and supplementary investigations in vitro.
Eur J Pharm Sci
; 47(1): 44-55, 2012 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-22579664
9.
Absorption, distribution, metabolism, and elimination of the direct renin inhibitor aliskiren in healthy volunteers.
Drug Metab Dispos
; 35(8): 1418-28, 2007 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-17510248
10.
Pimecrolimus: absorption, distribution, metabolism, and excretion in healthy volunteers after a single oral dose and supplementary investigations in vitro.
Drug Metab Dispos
; 34(5): 765-74, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16467136
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