Detalles de la búsqueda
1.
Phase 1 safety, tolerability, pharmacokinetics and pharmacodynamic results of KCL-286, a novel retinoic acid receptor-ß agonist for treatment of spinal cord injury, in male healthy participants.
Br J Clin Pharmacol
; 89(12): 3573-3583, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37452623
2.
Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells.
J Neurosci
; 39(16): 3013-3027, 2019 04 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-30760627
3.
The regulation of mitochondrial dynamics in neurite outgrowth by retinoic acid receptor ß signaling.
FASEB J
; 33(6): 7225-7235, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30857414
4.
Recent advances in the design of RAR α and RAR ß agonists as orally bioavailable drugs. A review.
Bioorg Med Chem
; 28(20): 115664, 2020 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33069074
5.
Discovery and lead optimisation of a potent, selective and orally bioavailable RARß agonist for the potential treatment of nerve injury.
Bioorg Med Chem Lett
; 29(8): 995-1000, 2019 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30792038
6.
Retinoic acid synthesis by NG2 expressing cells promotes a permissive environment for axonal outgrowth.
Neurobiol Dis
; 111: 70-79, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29274429
7.
Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist.
Bioorg Med Chem
; 26(4): 798-814, 2018 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29288071
8.
Neuronal RARß Signaling Modulates PTEN Activity Directly in Neurons and via Exosome Transfer in Astrocytes to Prevent Glial Scar Formation and Induce Spinal Cord Regeneration.
J Neurosci
; 35(47): 15731-45, 2015 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-26609164
9.
Corrigendum to "Discovery and lead optimisation of a potent, selective and orally bioavailable RARß agonist for the potential treatment of nerve injury" [Bioorg. Med. Chem. Lett. 29(8) (2019) 995-1000].
Bioorg Med Chem Lett
; 29(16): 2440-2441, 2019 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31208764
10.
Amyloid ß inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist.
Eur J Neurosci
; 37(7): 1182-92, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23379615
11.
RARß Agonist Drug (C286) Demonstrates Efficacy in a Pre-clinical Neuropathic Pain Model Restoring Multiple Pathways via DNA Repair Mechanisms.
iScience
; 20: 554-566, 2019 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-31655065
12.
RARß Agonist Drug (C286) Demonstrates Efficacy in a Pre-clinical Neuropathic Pain Model Restoring Multiple Pathways via DNA Repair Mechanisms.
iScience
; 21: 562-563, 2019 Nov 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-31726373
Resultados
1 -
12
de 12
1
Próxima >
>>