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1.
Population pharmacokinetics and site of action exposures of veliparib with topotecan plus carboplatin in patients with haematological malignancies.
Br J Clin Pharmacol
; 83(8): 1688-1700, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28156017
2.
Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia.
Blood
; 119(1): 55-63, 2012 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-22001391
3.
A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms.
Haematologica
; 99(4): 672-8, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24362550
4.
Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias.
Blood
; 117(12): 3302-10, 2011 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-21239698
5.
Phase 1 dose-escalation trial of clofarabine followed by escalating dose of fractionated cyclophosphamide in adults with relapsed or refractory acute leukaemias.
Br J Haematol
; 158(2): 198-207, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22594769
6.
Randomized phase II study of two schedules of flavopiridol given as timed sequential therapy with cytosine arabinoside and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia.
Haematologica
; 97(11): 1736-42, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22733022
7.
Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: a preclinical and phase 1 trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide.
Blood
; 113(20): 4841-52, 2009 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19109557
8.
Population pharmacokinetics and exposure-response assessment of veliparib co-administered with temozolomide in patients with myeloid leukemias.
Cancer Chemother Pharmacol
; 83(2): 319-328, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30456480
9.
Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure-FLT3 Relationship.
Clin Transl Sci
; 11(4): 435-443, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29702736
10.
Exposure-Response of Veliparib to Inform Phase II Trial Design in Refractory or Relapsed Patients with Hematological Malignancies.
Clin Cancer Res
; 23(21): 6421-6429, 2017 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28751440
11.
Exposure-Response Analysis of Alvocidib (Flavopiridol) Treatment by Bolus or Hybrid Administration in Newly Diagnosed or Relapsed/Refractory Acute Leukemia Patients.
Clin Cancer Res
; 23(14): 3592-3600, 2017 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28174232
12.
Phase I and pharmacologic trial of cytosine arabinoside with the selective checkpoint 1 inhibitor Sch 900776 in refractory acute leukemias.
Clin Cancer Res
; 18(24): 6723-31, 2012 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23092873
13.
Clinical activity of sequential flavopiridol, cytosine arabinoside, and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia.
Leuk Res
; 34(7): 877-82, 2010 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19962759
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