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1.
Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells.
Chembiochem
; 21(16): 2329-2347, 2020 08 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32227662
2.
Innovative strategies for adverse karyotype acute myeloid leukemia.
Curr Opin Hematol
; 24(2): 89-98, 2017 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28099271
3.
The pan-HDAC inhibitor panobinostat acts as a sensitizer for erlotinib activity in EGFR-mutated and -wildtype non-small cell lung cancer cells.
BMC Cancer
; 15: 947, 2015 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26675484
4.
Functional Characterization of Transforming Growth Factor-ß Signaling in Dasatinib Resistance and Pre-BCR+ Acute Lymphoblastic Leukemia.
Cancers (Basel)
; 15(17)2023 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37686604
5.
In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts.
Leukemia
; 37(5): 1018-1027, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37024521
6.
The antileukemic activity of decitabine upon PML/RARA-negative AML blasts is supported by all-trans retinoic acid: in vitro and in vivo evidence for cooperation.
Blood Cancer J
; 12(8): 122, 2022 08 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-35995769
7.
Hypomethylating agents (HMA) for the treatment of acute myeloid leukemia and myelodysplastic syndromes: mechanisms of resistance and novel HMA-based therapies.
Leukemia
; 35(7): 1873-1889, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33958699
8.
Decitabine Induces Gene Derepression on Monosomic Chromosomes: In Vitro and In Vivo Effects in Adverse-Risk Cytogenetics AML.
Cancer Res
; 81(4): 834-846, 2021 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33203699
9.
Integrative study of EZH2 mutational status, copy number, protein expression and H3K27 trimethylation in AML/MDS patients.
Clin Epigenetics
; 13(1): 77, 2021 04 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33845873
10.
Impact of the Injection Site on Growth Characteristics, Phenotype and Sensitivity towards Cytarabine of Twenty Acute Leukaemia Patient-Derived Xenograft Models.
Cancers (Basel)
; 12(5)2020 05 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32466316
11.
Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation.
Leukemia
; 33(4): 945-956, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30470836
12.
Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.
Leukemia
; 33(6): 1541, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-30837671
13.
LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.
Leukemia
; 33(6): 1411-1426, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30679800
14.
Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.
Eur J Med Chem
; 144: 52-67, 2018 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29247860
15.
Epigenetic therapy approaches in non-small cell lung cancer: Update and perspectives.
Epigenetics
; 11(12): 858-870, 2016 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27846368
16.
Correction to: Integrative study of EZH2 mutational status, copy number, protein expression and H3K27 trimethylation in AML/MDS patients.
Clin Epigenetics
; 13(1): 94, 2021 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33910627
17.
Epigenetic priming of non-small cell lung cancer cell lines to the antiproliferative and differentiating effects of all-trans retinoic acid.
J Cancer Res Clin Oncol
; 141(12): 2171-80, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26008188
18.
Identification of enhancer of mRNA decapping 4 as a novel fusion partner of MLL in acute myeloid leukemia.
Blood Adv
; 3(5): 761-765, 2019 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30833276
19.
Epigenetic priming of AML blasts for all-trans retinoic acid-induced differentiation by the HDAC class-I selective inhibitor entinostat.
PLoS One
; 8(10): e75258, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24116031
20.
Y-Chromosome variation in hominids: intraspecific variation is limited to the polygamous chimpanzee.
PLoS One
; 6(12): e29311, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22216243
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