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1.
Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-Gi Complex Structures.
Cell
; 180(4): 655-665.e18, 2020 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32004463
2.
G protein signaling-biased mu opioid receptor agonists that produce sustained G protein activation are noncompetitive agonists.
Proc Natl Acad Sci U S A
; 118(48)2021 11 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-34819362
3.
Probing the CB1 Cannabinoid Receptor Binding Pocket with AM6538, a High-Affinity Irreversible Antagonist.
Mol Pharmacol
; 96(5): 619-628, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31515283
4.
Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model.
J Pharmacol Exp Ther
; 363(3): 394-401, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28970359
5.
The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model.
J Pharmacol Exp Ther
; 357(1): 145-56, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26791602
6.
Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice.
J Pharmacol Exp Ther
; 352(2): 195-207, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25398241
7.
Full Fatty Acid Amide Hydrolase Inhibition Combined with Partial Monoacylglycerol Lipase Inhibition: Augmented and Sustained Antinociceptive Effects with Reduced Cannabimimetic Side Effects in Mice.
J Pharmacol Exp Ther
; 354(2): 111-20, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25998048
8.
Hyperactivity in Mice Induced by Opioid Agonists with Partial Intrinsic Efficacy and Biased Agonism Administered Alone and in Combination with Morphine.
Biomolecules
; 13(6)2023 06 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37371516
9.
Comparison of morphine, oxycodone and the biased MOR agonist SR-17018 for tolerance and efficacy in mouse models of pain.
Neuropharmacology
; 185: 108439, 2021 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33345829
10.
Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists.
J Med Chem
; 64(7): 3870-3884, 2021 04 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33761251
11.
Toward Directing Opioid Receptor Signaling to Refine Opioid Therapeutics.
Biol Psychiatry
; 87(1): 15-21, 2020 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31806082
12.
A G protein signaling-biased agonist at the µ-opioid receptor reverses morphine tolerance while preventing morphine withdrawal.
Neuropsychopharmacology
; 45(2): 416-425, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31443104
13.
Effectiveness comparisons of G-protein biased and unbiased mu opioid receptor ligands in warm water tail-withdrawal and drug discrimination in male and female rats.
Neuropharmacology
; 150: 200-209, 2019 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30660628
14.
The effect of quinine in two bottle choice procedures in C57BL6 mice: Opioid preference, somatic withdrawal, and pharmacokinetic outcomes.
Drug Alcohol Depend
; 191: 195-202, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30138791
15.
Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.
Nat Commun
; 8: 13958, 2017 01 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-28045021
16.
Pharmacological characterization of repeated administration of the first generation abused synthetic cannabinoid CP47,497.
J Basic Clin Physiol Pharmacol
; 27(3): 217-28, 2016 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27149200
17.
Effects of acute and repeated dosing of the synthetic cannabinoid CP55,940 on intracranial self-stimulation in mice.
Drug Alcohol Depend
; 150: 31-7, 2015 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25772438
18.
Combined inhibition of FAAH and COX produces enhanced anti-allodynic effects in mouse neuropathic and inflammatory pain models.
Pharmacol Biochem Behav
; 124: 405-11, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25058512
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