Detalles de la búsqueda
1.
Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.
Hum Mol Genet
; 28(13): 2120-2132, 2019 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30806670
2.
Combination of anthracyclines and anti-CD47 therapy inhibit invasive breast cancer growth while preventing cardiac toxicity by regulation of autophagy.
Breast Cancer Res Treat
; 172(1): 69-82, 2018 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30056566
3.
Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.
PLoS Pathog
; 12(6): e1005717, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27336364
4.
SU9516 Increases α7ß1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy.
Mol Ther
; 25(6): 1395-1407, 2017 06 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28391962
5.
Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia.
Proc Natl Acad Sci U S A
; 112(40): 12480-5, 2015 Oct 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26396258
6.
Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.
Proc Natl Acad Sci U S A
; 111(31): 11365-70, 2014 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-25049379
7.
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cells.
Proc Natl Acad Sci U S A
; 111(6): 2349-54, 2014 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24469833
8.
Scaffolding Protein Connector Enhancer of Kinase Suppressor of Ras 1 (CNKSR1) Regulates MAPK Inhibition Responsiveness in Pancreas Cancer via Crosstalk with AKT Signaling.
Mol Cancer Res
; 21(4): 316-331, 2023 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36790955
9.
Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
Cell Chem Biol
; 30(9): 1156-1168.e7, 2023 09 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37689063
10.
Screening in serum-derived medium reveals differential response to compounds targeting metabolism.
bioRxiv
; 2023 Feb 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36909640
11.
Discovery and Optimization of Pyrrolopyrimidine Derivatives as Selective Disruptors of the Perinucleolar Compartment, a Marker of Tumor Progression toward Metastasis.
J Med Chem
; 65(12): 8303-8331, 2022 06 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-35696646
12.
LXH254, a Potent and Selective ARAF-Sparing Inhibitor of BRAF and CRAF for the Treatment of MAPK-Driven Tumors.
Clin Cancer Res
; 27(7): 2061-2073, 2021 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33355204
13.
Identification of Small Molecule Enhancers of Immunotherapy for Melanoma.
Sci Rep
; 10(1): 5688, 2020 03 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-32231230
14.
Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis.
Cancer Res
; 80(12): 2689-2702, 2020 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32341035
15.
Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide, a Selective, Efficacious, and Well-Tolerated RAF Inhibitor Targeting RAS Mutant Cancers: The Path to the Clinic.
J Med Chem
; 63(5): 2013-2027, 2020 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31059256
16.
Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors.
Front Oncol
; 9: 994, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31632920
17.
Target Deconvolution of a Multikinase Inhibitor with Antimetastatic Properties Identifies TAOK3 as a Key Contributor to a Cancer Stem Cell-Like Phenotype.
Mol Cancer Ther
; 18(11): 2097-2110, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31395684
18.
Mutation Profiles in Glioblastoma 3D Oncospheres Modulate Drug Efficacy.
SLAS Technol
; 24(1): 28-40, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30289729
19.
Generation of High-Throughput Three-Dimensional Tumor Spheroids for Drug Screening.
J Vis Exp
; (139)2018 09 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30247463
20.
Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAF.
Cancer Res
; 78(6): 1537-1548, 2018 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29343524