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1.
Positive allosteric modulators of the α7 nicotinic acetylcholine receptor: SAR investigation around PNU-120596.
Bioorg Med Chem Lett
; 93: 129433, 2023 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37557923
2.
Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1.
J Clin Invest
; 132(11)2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35439173
3.
Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders.
J Med Chem
; 62(10): 4884-4901, 2019 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31013090
4.
Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity.
Bioorg Med Chem Lett
; 18(12): 3611-5, 2008 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18490160
5.
Phenotypic Optimization of Urea-Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss.
J Med Chem
; 61(1): 84-97, 2018 01 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28992413
6.
A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.
J Neurosci
; 25(17): 4396-405, 2005 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-15858066
7.
Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship.
J Med Chem
; 49(14): 4425-36, 2006 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-16821801
8.
High-Throughput Screening for Drugs that Modulate Intermediate Filament Proteins.
Methods Enzymol
; 568: 163-85, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26795471
9.
Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.
J Med Chem
; 48(4): 905-8, 2005 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15715459
10.
Pharmacologic characterization of a kinetic in vitro human co-culture angiogenesis model using clinically relevant compounds.
J Biomol Screen
; 18(10): 1234-45, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24019254
11.
Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists.
Bioorg Med Chem
; 14(24): 8219-48, 2006 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17011782
12.
High-affinity epibatidine binding of functional, human alpha7-nicotinic acetylcholine receptors stably and heterologously expressed de novo in human SH-EP1 cells.
J Pharmacol Exp Ther
; 313(1): 24-35, 2005 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-15590768
13.
Anthelmintic paraherquamides are cholinergic antagonists in gastrointestinal nematodes and mammals.
J Vet Pharmacol Ther
; 25(4): 241-50, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12213111
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