Detalles de la búsqueda
1.
Extended lifespan and improved genome stability in HepaRG-derived cell lines through reprogramming by high-density stress.
Proc Natl Acad Sci U S A
; 120(36): e2219298120, 2023 09 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37639591
2.
Progressive and Preferential Cellular Accumulation of Hydrophobic Bile Acids Induced by Cholestatic Drugs Is Associated with Inhibition of Their Amidation and Sulfation.
Drug Metab Dispos
; 45(12): 1292-1303, 2017 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-28928138
3.
Hepatic differentiation of human pluripotent stem cells on human liver progenitor HepaRG-derived acellular matrix.
Exp Cell Res
; 341(2): 207-17, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26854693
4.
Early Alterations of Bile Canaliculi Dynamics and the Rho Kinase/Myosin Light Chain Kinase Pathway Are Characteristics of Drug-Induced Intrahepatic Cholestasis.
Drug Metab Dispos
; 44(11): 1780-1793, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27538918
5.
Functional polymer-dependent 3D culture accelerates the differentiation of HepaRG cells into mature hepatocytes.
Hepatol Res
; 46(10): 1045-57, 2016 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26724677
6.
Liver X receptor α (LXRα/NR1H3) regulates differentiation of hepatocyte-like cells via reciprocal regulation of HNF4α.
J Hepatol
; 61(6): 1276-86, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25073010
7.
Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells.
Hepatology
; 57(4): 1518-29, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23175273
8.
Impact of inflammation on chlorpromazine-induced cytotoxicity and cholestatic features in HepaRG cells.
Drug Metab Dispos
; 42(9): 1556-66, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25002748
9.
The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice.
Xenobiotica
; 44(2): 146-53, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24066694
10.
The promoter of human telomerase reverse transcriptase is activated during liver regeneration and hepatocyte proliferation.
Gastroenterology
; 141(1): 326-37, 337.e1-3, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21447332
11.
CYP4F3B expression is associated with differentiation of HepaRG human hepatocytes and unaffected by fatty acid overload.
Drug Metab Dispos
; 39(10): 1987-96, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21778351
12.
Reperfusion stress induced during intermittent selective clamping accelerates rat liver regeneration through JNK pathway.
J Hepatol
; 52(4): 560-9, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20207439
13.
Cyclin-dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration.
Hepatology
; 50(6): 1946-56, 2009 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19821535
14.
Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells.
Drug Metab Dispos
; 38(3): 516-25, 2010 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-20019244
15.
Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells.
Toxicol Appl Pharmacol
; 245(2): 256-63, 2010 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20307560
16.
Electrochemical synthesis and characterisation of alternating tripyridyl-dipyrrole molecular strands with multiple nitrogen-based donor-acceptor binding sites.
Chemistry
; 16(39): 11876-89, 2010 Oct 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-20839373
17.
Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays.
Mutagenesis
; 25(6): 555-60, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20675360
18.
Synthesis and kinase inhibitory activity of novel substituted indigoids.
Bioorg Med Chem
; 17(17): 6257-63, 2009 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19665384
19.
Setup and Use of HepaRG Cells in Cholestasis Research.
Methods Mol Biol
; 1981: 291-312, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31016662
20.
Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential.
Toxicol Sci
; 168(2): 474-485, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30629237