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1.
Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.
Mol Cell
; 77(6): 1251-1264.e9, 2020 03 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-32023484
2.
Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry.
Bioorg Med Chem
; 42: 116223, 2021 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34091303
3.
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology.
Proc Natl Acad Sci U S A
; 113(49): E7880-E7889, 2016 12 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27864515
4.
Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry.
Molecules
; 24(10)2019 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-31137911
5.
Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus.
Proc Natl Acad Sci U S A
; 110(18): 7452-7, 2013 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-23569269
6.
Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.
ACS Infect Dis
; 10(5): 1561-1575, 2024 05 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-38577994
7.
Development of Potent Mcl-1 Inhibitors: Structural Investigations on Macrocycles Originating from a DNA-Encoded Chemical Library Screen.
J Med Chem
; 67(4): 3039-3065, 2024 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-38306405
8.
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds.
J Med Chem
; 67(8): 6456-6494, 2024 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38574366
9.
Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning.
J Med Chem
; 66(23): 16051-16061, 2023 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37996079
10.
Discovery of Nanomolar DCAF1 Small Molecule Ligands.
J Med Chem
; 66(7): 5041-5060, 2023 04 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36948210
11.
Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding.
J Med Chem
; 63(16): 8857-8866, 2020 08 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32525674
12.
Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target.
SLAS Discov
; 23(5): 429-436, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29316408
13.
Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library.
Sci Rep
; 5: 10916, 2015 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26061191
14.
Synthesis and preliminary in vitro evaluation of antimycobacterial activity of new pyrrolo[1,2-a] quinoxaline-carboxylic acid hydrazide derivatives.
J Enzyme Inhib Med Chem
; 19(6): 489-95, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15662953
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