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1.
Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects.
J Med Chem
; 49(4): 1223-6, 2006 Feb 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-16480257
2.
Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism.
J Mol Biol
; 331(2): 407-16, 2003 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-12888348
3.
Iminosugars as glycosyltransferase inhibitors: synthesis of polyhydroxypyrrolidines and their evaluation on chitin synthase activity.
Eur J Med Chem
; 40(12): 1255-61, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16095761
4.
Structures of 5-methylthioribose kinase reveal substrate specificity and unusual mode of nucleotide binding.
J Biol Chem
; 282(30): 22195-206, 2007 Jul 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-17522047
5.
Inactivation of S-adenosylhomocysteine hydrolase with haloethyl and dihalocyclopropyl esters derived from homoadenosine-6'-carboxylic acid.
Bioorg Med Chem Lett
; 14(23): 5799-802, 2004 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-15501043
6.
Inactivation of human S-adenosylhomocysteine hydrolase by covalent labeling of cysteine 195 with thionucleoside derivatives.
Bioorg Med Chem Lett
; 14(23): 5803-7, 2004 Dec 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-15501044
7.
Design, synthesis and biological evaluation of hetaryl-nucleoside derivatives as inhibitors of chitin synthase.
Bioorg Med Chem Lett
; 13(10): 1713-6, 2003 May 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-12729648
8.
Inactivation of S-adenosyl-L-homocysteine hydrolase with novel 5'-thioadenosine derivatives. Antiviral effects.
Bioorg Med Chem Lett
; 13(10): 1649-52, 2003 May 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-12729633
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