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1.
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Gastroenterology
; 142(1): 140-151.e12, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22001865
2.
Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology
; 56(1): 270-80, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22271167
3.
Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCOâ»3 output.
Hepatology
; 54(4): 1303-12, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22006858
4.
Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Gastroenterology
; 138(7): 2499-508, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20193684
5.
Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.
Hepatology
; 51(4): 1319-26, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20162728
6.
Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.
Gut
; 59(4): 521-30, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20332524
7.
The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice.
Lab Invest
; 90(6): 844-52, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-20368698
8.
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Hepatology
; 49(6): 1972-81, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19475687
9.
Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
Trop Med Int Health
; 14(11): 1418-25, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19747186
10.
Impact of experimental colitis on hepatobiliary transporter expression and bile duct injury in mice.
Liver Int
; 29(9): 1316-25, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19558576
11.
Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice.
Liver Int
; 28(7): 948-58, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18410282
12.
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver Int
; 27(7): 920-9, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17696930
13.
Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress.
Drug Metab Dispos
; 35(9): 1694-9, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17576807
14.
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol
; 290(5): G923-32, 2006 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-16357057
15.
Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
J Lipid Res
; 47(3): 582-92, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16327028
16.
Successful treatment of severe unconjugated hyperbilirubinemia via induction of UGT1A1 by rifampicin.
J Hepatol
; 44(1): 243-5, 2006 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-16288819
17.
Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Am J Physiol Gastrointest Liver Physiol
; 289(5): G798-805, 2005 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-16002565
18.
Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.
Gastroenterology
; 129(2): 476-85, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16083704
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