Detalles de la búsqueda
1.
Discovery of 5-(3-bromo-2-(2,3-dibromo-4,5-dimethoxybenzyl)-4,5-dimethoxybenzylidene)thiazolidine-2,4-dione as a novel potent protein tyrosine phosphatase 1B inhibitor with antidiabetic properties.
Bioorg Chem
; 108: 104648, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33493928
2.
16S rRNA Sequencing and Metagenomics Study of Gut Microbiota: Implications of BDB on Type 2 Diabetes Mellitus.
Mar Drugs
; 18(9)2020 Sep 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32957565
3.
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction.
Int J Mol Sci
; 21(3)2020 Feb 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32033205
4.
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.
Mol Pharm
; 16(5): 1839-1850, 2019 05 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30974944
5.
Discovery of Natural Dimeric Naphthopyrones as Potential Cytotoxic Agents Through ROS-Mediated Apoptotic Pathway.
Mar Drugs
; 17(4)2019 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30987066
6.
Design and Synthesis of a Fluorescent Probe with a Large Stokes Shift for Detecting Thiophenols and Its Application in Water Samples and Living Cells.
Molecules
; 24(2)2019 Jan 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-30669672
7.
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors.
Bioorg Med Chem Lett
; 28(12): 2131-2135, 2018 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29773502
8.
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway.
Mar Drugs
; 16(2)2018 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29370087
9.
A novel fluorinated thiosemicarbazone derivative- 2-(3,4-difluorobenzylidene) hydrazinecarbothioamide induces apoptosis in human A549 lung cancer cells via ROS-mediated mitochondria-dependent pathway.
Biochem Biophys Res Commun
; 491(1): 65-71, 2017 09 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28698138
10.
Design of antitumor agents containing carbohydrate based on GLUT1, and evaluation of antiproliferative activity.
Bioorg Med Chem Lett
; 27(11): 2488-2492, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28462838
11.
Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation.
Mar Drugs
; 15(11)2017 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29104274
12.
HPN, a synthetic analogue of bromophenol from red alga Rhodomela confervoides: synthesis and anti-diabetic effects in C57BL/KsJ-db/db mice.
Mar Drugs
; 11(2): 350-62, 2013 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-23364683
13.
Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties.
Bioorg Med Chem Lett
; 22(8): 2827-32, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22444684
14.
Design, synthesis, and biological evaluation of bromophenol derivatives as protein tyrosine phosphatase 1B inhibitors.
Arch Pharm (Weinheim)
; 345(6): 444-53, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22307562
15.
A novel dibenzo[a,c]phenazine-based fluorescent probe for fast and selective detection of thiophenols in environmental water.
RSC Adv
; 12(14): 8611-8616, 2022 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35424794
16.
Adonis amurensis Is a Promising Alternative to Haematococcus as a Resource for Natural Esterified (3S,3'S)-Astaxanthin Production.
Plants (Basel)
; 10(6)2021 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34070556
17.
DFT and Raman study of all-trans astaxanthin optical isomers.
Spectrochim Acta A Mol Biomol Spectrosc
; 262: 120143, 2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34271237
18.
Effects of a natural PTP1B inhibitor from Rhodomela confervoides on the amelioration of fatty acid-induced insulin resistance in hepatocytes and hyperglycaemia in STZ-induced diabetic rats.
RSC Adv
; 10(6): 3429-3437, 2020 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35497760
19.
Binding properties of marine bromophenols with human protein tyrosine phosphatase 1B: Molecular docking, surface plasmon resonance and cellular insulin resistance study.
Int J Biol Macromol
; 163: 200-208, 2020 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32619661
20.
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, from Rhodomela confervoides.
Br J Pharmacol
; 177(19): 4464-4480, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32663313