Detalles de la búsqueda
1.
Prognosis in moderate-severe traumatic brain injury in a Swedish cohort and external validation of the IMPACT models.
Acta Neurochir (Wien)
; 164(3): 615-624, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34936014
2.
Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function.
J Biol Chem
; 295(15): 5136-5151, 2020 04 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32132173
3.
The Role of BDNF in Experimental and Clinical Traumatic Brain Injury.
Int J Mol Sci
; 22(7)2021 Mar 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-33808272
4.
Development of Human Target Validation Classification that Predicts Future Clinical Efficacy.
J Pharmacol Exp Ther
; 368(2): 255-261, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30482795
5.
Discovery and Evaluation of Anti-Fibrinolytic Plasmin Inhibitors Derived from 5-(4-Piperidyl)isoxazol-3-ol (4-PIOL).
J Chem Inf Model
; 57(7): 1703-1714, 2017 07 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-28653850
6.
Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation.
J Biol Chem
; 288(2): 873-85, 2013 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-23155046
7.
Translational success stories: development of direct thrombin inhibitors.
Circ Res
; 111(7): 920-9, 2012 Sep 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-22982873
8.
Design, synthesis, and SAR of a series of activated protein C (APC) inhibitors with selectivity against thrombin for the treatment of haemophilia.
Bioorg Med Chem Lett
; 24(3): 821-7, 2014 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24418773
9.
Ticagrelor reduces neutrophil recruitment and lung damage in abdominal sepsis.
Platelets
; 25(4): 257-63, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-23855479
10.
The pathophysiology of hyperuricaemia and its possible relationship to cardiovascular disease, morbidity and mortality.
BMC Nephrol
; 14: 164, 2013 Jul 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-23895142
11.
The modified Medical Research Council scale misclassifies exertional breathlessness among people referred for exercise testing.
ERJ Open Res
; 9(6)2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-38152083
12.
From natural products to achiral drug prototypes: potent thrombin inhibitors based on P2/P3 dihydropyrid-2-one core motifs.
Bioorg Med Chem Lett
; 19(18): 5429-32, 2009 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19674897
13.
Plasminogen binding inhibitors demonstrate unwanted activities on GABAA and glycine receptors in human iPSC derived neurons.
Neurosci Lett
; 681: 37-43, 2018 08 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29758302
14.
A Vertical Organic Transistor Architecture for Fast Nonvolatile Memory.
Adv Mater
; 29(8)2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-28004860
15.
Modeling carbon turnover in five terrestrial ecosystems in the boreal zone using multiple criteria of acceptance.
Ambio
; 35(8): 448-58, 2006 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17334052
16.
Macrocyclic Prodrugs of a Selective Nonpeptidic Direct Thrombin Inhibitor Display High Permeability, Efficient Bioconversion but Low Bioavailability.
J Med Chem
; 59(14): 6658-70, 2016 07 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-27347787
17.
Effects of ximelagatran, an oral direct thrombin inhibitor, r-hirudin and enoxaparin on thrombin generation and platelet activation in healthy male subjects.
J Am Coll Cardiol
; 41(4): 557-64, 2003 Feb 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-12598065
18.
Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design.
PLoS One
; 10(1): e0113705, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25629509
19.
Inhibition of thrombin generation by the oral direct thrombin inhibitor ximelagatran in shed blood from healthy male subjects.
Thromb Haemost
; 87(2): 300-5, 2002 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-11858491
20.
A dose-ranging study of the oral direct thrombin inhibitor, ximelagatran, and its subcutaneous form, melagatran, compared with dalteparin in the prophylaxis of thromboembolism after hip or knee replacement: METHRO I. MElagatran for THRombin inhibition in Orthopaedic surgery.
Thromb Haemost
; 87(2): 231-7, 2002 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-11858482