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1.
The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profile.
BMC Endocr Disord
; 21(1): 10, 2021 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33413317
2.
Optimization of tolerability and efficacy of the novel dual amylin and calcitonin receptor agonist KBP-089 through dose escalation and combination with a GLP-1 analog.
Am J Physiol Endocrinol Metab
; 313(5): E598-E607, 2017 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28292761
3.
The Dual Amylin- and Calcitonin-Receptor Agonist KBP-042 Works as Adjunct to Metformin on Fasting Hyperglycemia and HbA1c in a Rat Model of Type 2 Diabetes.
J Pharmacol Exp Ther
; 362(1): 24-30, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28438778
4.
KBP-088, a novel DACRA with prolonged receptor activation, is superior to davalintide in terms of efficacy on body weight.
Am J Physiol Endocrinol Metab
; 310(10): E821-7, 2016 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26908506
5.
A novel oral dual amylin and calcitonin receptor agonist (KBP-042) exerts antiobesity and antidiabetic effects in rats.
Am J Physiol Endocrinol Metab
; 307(1): E24-33, 2014 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24801386
6.
A novel dual amylin and calcitonin receptor agonist, KBP-089, induces weight loss through a reduction in fat, but not lean mass, while improving food preference.
Br J Pharmacol
; 174(7): 591-602, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28109166
7.
The dual amylin- and calcitonin-receptor agonist KBP-042 increases insulin sensitivity and induces weight loss in rats with obesity.
Obesity (Silver Spring)
; 24(8): 1712-22, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27296301
8.
KBP-042 improves bodyweight and glucose homeostasis with indices of increased insulin sensitivity irrespective of route of administration.
Eur J Pharmacol
; 762: 229-38, 2015 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-26027795
9.
Oral salmon calcitonin enhances insulin action and glucose metabolism in diet-induced obese streptozotocin-diabetic rats.
Eur J Pharmacol
; 737: 91-6, 2014 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24858364
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