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1.
Synthesis and metabotropic glutamate receptor activity of S-oxidized variants of (-)-4-amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate: identification of potent, selective, and orally bioavailable agonists for mGlu2/3 receptors.
J Med Chem
; 50(2): 233-40, 2007 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-17228865
2.
Dipeptides as effective prodrugs of the unnatural amino acid (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740), a selective group II metabotropic glutamate receptor agonist.
J Med Chem
; 48(16): 5305-20, 2005 Aug 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-16078848
3.
Synthesis and pharmacological characterization of 4-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates: identification of new potent and selective metabotropic glutamate 2/3 receptor agonists.
J Med Chem
; 56(11): 4442-55, 2013 Jun 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-23675965
4.
Pharmacological and pharmacokinetic properties of a structurally novel, potent, and selective metabotropic glutamate 2/3 receptor agonist: in vitro characterization of agonist (-)-(1R,4S,5S,6S)-4-amino-2-sulfonylbicyclo[3.1.0]-hexane-4,6-dicarboxylic acid (LY404039).
J Pharmacol Exp Ther
; 321(1): 308-17, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17204749
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