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1.
New investigations into the genotoxicity of cobalt compounds and their impact on overall assessment of genotoxic risk.
Regul Toxicol Pharmacol
; 73(1): 311-38, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26210821
2.
A novel series of metabotropic glutamate receptor 5 negative allosteric modulators based on a 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine core.
Bioorg Med Chem Lett
; 23(16): 4523-7, 2013 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23850200
3.
Mutagenicity of benzyl chloride in the Salmonella/microsome mutagenesis assay depends on exposure conditions.
Mutat Res
; 633(1): 13-20, 2007 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17631040
4.
ADX71943 and ADX71441, novel positive allosteric modulators of the GABAB receptor with distinct central/peripheral profiles, show efficacy in the monosodium iodoacetate model of chronic osteoarthritis pain in the rat.
Eur J Pharmacol
; 795: 43-49, 2017 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27916555
5.
The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABAB receptor with a potential for treatment of anxiety, pain and spasticity.
Neuropharmacology
; 114: 34-47, 2017 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27889489
6.
Reduction of excessive alcohol drinking by a novel GABAB receptor positive allosteric modulator ADX71441 in mice.
Psychopharmacology (Berl)
; 231(2): 333-43, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23975038
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