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1.
Clinical pharmacokinetics and pharmacodynamics of empagliflozin in patients with heart failure.
Br J Clin Pharmacol
; 2024 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38852615
2.
ICH M9 Guideline in Development on Biopharmaceutics Classification System-Based Biowaivers: An Industrial Perspective from the IQ Consortium.
Mol Pharm
; 17(2): 361-372, 2020 02 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31846335
3.
Genetic determinants of dabigatran plasma levels and their relation to bleeding.
Circulation
; 127(13): 1404-12, 2013 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-23467860
4.
Association between statin use and ischemic stroke or major hemorrhage in patients taking dabigatran for atrial fibrillation.
CMAJ
; 189(8): E325, 2017 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-28246231
5.
To blind or not to blind first in human and exploratory clinical trials: Acceleration of development vs. risk of bias.
Clin Transl Sci
; 15(3): 601-609, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34786861
6.
Roadmap to 2030 for Drug Evaluation in Older Adults.
Clin Pharmacol Ther
; 112(2): 210-223, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34656074
7.
Population in vitro-in vivo correlation model for pramipexole slow-release oral formulations.
Pharm Res
; 27(2): 340-9, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-20039105
8.
Correction to: How is the Pharmaceutical Industry Structured to Optimize Pediatric Drug Development? Existing Pediatric Structure Models and Proposed Recommendations for Structural Enhancement.
Ther Innov Regul Sci
; 54(5): 1085, 2020 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-32865808
9.
How is the Pharmaceutical Industry Structured to Optimize Pediatric Drug Development? Existing Pediatric Structure Models and Proposed Recommendations for Structural Enhancement.
Ther Innov Regul Sci
; 54(5): 1076-1084, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32030690
10.
Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop.
Clin Pharmacol Ther
; 108(1): 29-39, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32017043
11.
Challenges and Opportunities in the Development of Medical Therapies for Pediatric Populations and the Role of Extrapolation.
Clin Pharmacol Ther
; 103(3): 419-433, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29277892
12.
Effect of Steady-State Faldaprevir on Pharmacokinetics of Atorvastatin or Rosuvastatin in Healthy Volunteers: A Prospective Open-Label, Fixed-Sequence Crossover Study.
J Clin Pharmacol
; 57(10): 1305-1314, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28513969
13.
An open-label study of the pharmacokinetics and pharmacodynamics of dabigatran etexilate 150mg once daily in Caucasian patients with moderate renal impairment undergoing primary unilateral elective total knee or hip replacement surgery.
Thromb Res
; 144: 158-64, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-27352238
14.
Safety, tolerability and clinical pharmacology of dabigatran etexilate in adolescents. An open-label phase IIa study.
Thromb Haemost
; 116(3): 461-71, 2016 08 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-27357738
15.
Selective impairment in sympathetic vasomotor control with norepinephrine transporter inhibition.
Circulation
; 107(23): 2949-54, 2003 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-12796139
16.
Influence of St John's wort on catecholamine turnover and cardiovascular regulation in humans.
Clin Pharmacol Ther
; 76(5): 480-9, 2004 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-15536462
17.
The effect of dabigatran plasma concentrations and patient characteristics on the frequency of ischemic stroke and major bleeding in atrial fibrillation patients: the RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulation Therapy).
J Am Coll Cardiol
; 63(4): 321-8, 2014 Feb 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-24076487
18.
Recent examples on the clinical relevance of the CYP2D6 polymorphism and endogenous functionality of CYP2D6.
Drug Metabol Drug Interact
; 28(4): 209-16, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24088607
19.
Dabigatran etexilate in atrial fibrillation patients with severe renal impairment: dose identification using pharmacokinetic modeling and simulation.
J Clin Pharmacol
; 52(9): 1373-8, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21956604
20.
Twice daily dosing of dabigatran for stroke prevention in atrial fibrillation: a pharmacokinetic justification.
Curr Med Res Opin
; 28(2): 195-201, 2012 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22208675