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Immunomodulatory drugs (IMiDs) increase the production of IL-2 from stimulated T cells by increasing PKC-theta activation and enhancing the DNA-binding activity of AP-1 but not NF-kappaB, OCT-1, or NF-AT.
J Interferon Cytokine Res
; 25(10): 604-16, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16241859
2.
Immunomodulatory drugs inhibit expression of cyclooxygenase-2 from TNF-alpha, IL-1beta, and LPS-stimulated human PBMC in a partially IL-10-dependent manner.
Cell Immunol
; 230(2): 81-8, 2004 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15598423
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