Detalles de la búsqueda
1.
Metformin and 2-Deoxyglucose Collaboratively Suppress Human CD4+ T Cell Effector Functions and Activation-Induced Metabolic Reprogramming.
J Immunol
; 205(4): 957-967, 2020 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32641388
2.
Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Immunity
; 35(2): 194-207, 2011 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-21820332
3.
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation.
J Immunol
; 197(6): 2421-33, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27521339
4.
An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice.
Kidney Int
; 90(3): 525-39, 2016 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27262364
5.
TRIL is involved in cytokine production in the brain following Escherichia coli infection.
J Immunol
; 193(4): 1911-9, 2014 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25015823
6.
Human Recombinant Alkaline Phosphatase (Ilofotase Alfa) Protects Against Kidney Ischemia-Reperfusion Injury in Mice and Rats Through Adenosine Receptors.
Front Med (Lausanne)
; 9: 931293, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35966871
7.
Identification and SAR of a new series of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitors.
Bioorg Med Chem Lett
; 21(19): 5952-6, 2011 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21862328
8.
Discovery of indazoles as inhibitors of Tpl2 kinase.
Bioorg Med Chem Lett
; 21(16): 4758-61, 2011 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21742493
9.
TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines.
Rheumatology (Oxford)
; 48(11): 1352-8, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19713442
10.
Optimized protocols for studying the NLRP3 inflammasome and assessment of potential targets of CP-453,773 in undifferentiated THP1 cells.
J Immunol Methods
; 467: 19-28, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30735689
11.
Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor alpha (TNF-alpha) production: selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3-carbonitriles.
J Med Chem
; 50(19): 4728-45, 2007 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-17715908
12.
A rat pharmacokinetic/pharmacodynamic model for assessment of lipopolysaccharide-induced tumor necrosis factor-alpha production.
J Pharmacol Toxicol Methods
; 56(1): 67-71, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17391989
13.
Corrigendum to "Optimized protocols for studying the NLRP3 inflammasome and assessment of potential targets of CP-453,773 in undifferentiated THP1 cells" [Journal of Immunological Methods 467 (2019) 19-28].
J Immunol Methods
; 468: 67, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-30947983
14.
Stimulation of TLR4 by recombinant HSP70 requires structural integrity of the HSP70 protein itself.
J Inflamm (Lond)
; 9: 11, 2012 Mar 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22448747
15.
Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.
J Leukoc Biol
; 88(6): 1171-80, 2010 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-20651301
16.
Analysis of c-Jun N-terminal kinase regulation and function.
Methods Enzymol
; 345: 413-25, 2002.
Artículo
en Inglés
| MEDLINE | ID: mdl-11665625
17.
Identification of a novel class of selective Tpl2 kinase inhibitors: 4-Alkylamino-[1,7]naphthyridine-3-carbonitriles.
Bioorg Med Chem
; 15(19): 6425-42, 2007 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17664070
18.
Pharmacologic inhibition of tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood.
J Biol Chem
; 282(46): 33295-33304, 2007 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-17848581
19.
Inhibition of Tpl2 kinase and TNFalpha production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis.
Bioorg Med Chem Lett
; 16(23): 6067-72, 2006 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16973359
20.
Inhibition of Tpl2 kinase and TNF-alpha production with 1,7-naphthyridine-3-carbonitriles: synthesis and structure-activity relationships.
Bioorg Med Chem Lett
; 15(23): 5288-92, 2005 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16165349