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1.
Use of an inverse agonist radioligand [3H]A-317920 reveals distinct pharmacological profiles of the rat histamine H3 receptor.
Neuropharmacology
; 50(4): 468-78, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16316670
2.
The challenge of drug discovery of a GPCR target: analysis of preclinical pharmacology of histamine H3 antagonists/inverse agonists.
Biochem Pharmacol
; 71(8): 1103-13, 2006 Apr 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-16513092
3.
Molecular modeling and pharmacological analysis of species-related histamine H(3) receptor heterogeneity.
Neuropharmacology
; 44(6): 773-86, 2003 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-12681376
4.
Synthesis and structure activity relationships of cis- and trans-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridines for 5-HT receptor subtypes.
J Med Chem
; 37(1): 105-12, 1994 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-8289183
5.
Conformationally defined adrenergic agents. 5. Resolution, absolute configuration, and pharmacological characterization of the enantiomers of 2-(5,6-dihydroxy-1,2,3,4-tetrahydro-1-naphthyl)imidazoline: a potent agonist at alpha-adrenoceptors.
J Med Chem
; 30(6): 1011-7, 1987 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-2884313
6.
Synthesis and in vitro characterization of N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: a novel selective alpha 1A receptor agonist.
J Med Chem
; 39(20): 4116-9, 1996 Sep 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-8831777
7.
Structure-activity studies for a novel series of N-(arylethyl)-N-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)-N-methylamine s possessing dual 5-HT uptake inhibiting and alpha2-antagonistic activities.
J Med Chem
; 40(7): 1049-62, 1997 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-9089327
8.
Structure-activity studies for a novel series of tricyclic substituted hexahydrobenz[e]isoindole alpha(1A) adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia (BPH).
J Med Chem
; 43(8): 1586-603, 2000 Apr 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-10780916
9.
Structure-activity studies for a novel series of bicyclic substituted hexahydrobenz[e]isoindole alpha1A adrenoceptor antagonists as potential agents for the symptomatic treatment of benign prostatic hyperplasia.
J Med Chem
; 44(12): 1971-85, 2001 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-11384242
10.
Alpha 1-adrenoceptor-induced contractility in rat aorta is mediated by the alpha 1D subtype.
Eur J Pharmacol
; 297(3): 241-8, 1996 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-8666056
11.
[3H]R-terazosin binds selectively to alpha1-adrenoceptors over alpha2-adrenoceptors - comparison with racemic [3H]terazosin and [3H]prazosin.
Eur J Pharmacol
; 327(1): 79-86, 1997 May 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-9185839
12.
Species-related pharmacological heterogeneity of histamine H(3) receptors.
Eur J Pharmacol
; 433(2-3): 141-50, 2001 Dec 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-11755145
13.
[3H]A-81988, a potent, selective, competitive antagonist radioligand for angiotensin AT1 receptors.
Eur J Pharmacol
; 267(1): 49-54, 1994 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-8206129
14.
Pharmacological characterization of Abbott-81282, a novel, non-peptide angiotensin-II antagonist selective for type-1 receptors.
Life Sci
; 53(11): 929-37, 1993.
Artículo
en Inglés
| MEDLINE | ID: mdl-8366760
15.
Histaminergic ligands attenuate barrel rotation in rats following unilateral labyrinthectomy.
Methods Find Exp Clin Pharmacol
; 20(9): 771-7, 1998 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-10022031
16.
Data normalization before statistical analysis: keeping the horse before the cart.
Trends Pharmacol Sci
; 9(1): 29-32, 1988 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-3245075
17.
Synthesis and pharmacological characterization of 3-[2-((3aR,9bR)-cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e] isoindol-2-yl)ethyl]pyrido-[3',4':4,5]thieno[3,2-d]pyrimidine-2,4 (1H,3H)-dione (A-131701): a uroselective alpha 1A adrenoceptor antagonist for the symptomatic treatment of benign prostatic hyperplasia.
J Med Chem
; 40(20): 3141-3, 1997 Sep 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-9379432
18.
Verapamil-induced changes in myocardial contractile force and cyclic nucleotides in the isolated perfused rat heart.
Biochem Pharmacol
; 28(17): 2601-6, 1979 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-229858
19.
A rapid, economical technique for removing radioactivity from receptor binding assay aqueous wastes.
Health Phys
; 47(4): 640-1, 1984 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-6511409
20.
Analysis of the hypotensive effects of medroxalol and its enantiomers, MDL 17,330A and MDL 17,331A.
Clin Exp Hypertens A
; 6(3): 659-84, 1984.
Artículo
en Inglés
| MEDLINE | ID: mdl-6144408