Detalles de la búsqueda
1.
Survey of Pharmaceutical Industry's Best Practices around In Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group.
Drug Metab Dispos
; 52(7): 582-596, 2024 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38697852
2.
Disposition of asciminib, a potent BCR-ABL1 tyrosine kinase inhibitor, in healthy male subjects.
Xenobiotica
; 50(2): 150-169, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31006307
3.
A Systematic In Vitro Investigation of the Inhibitor Preincubation Effect on Multiple Classes of Clinically Relevant Transporters.
Drug Metab Dispos
; 47(7): 768-778, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31068368
4.
Intestinal Transporter-Associated Drug Absorption and Toxicity.
Adv Exp Med Biol
; 1141: 361-405, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31571170
5.
Transport properties of valsartan, sacubitril and its active metabolite (LBQ657) as determinants of disposition.
Xenobiotica
; 48(3): 300-313, 2018 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-28281384
6.
Fevipiprant (QAW039) does not affect the pharmacokinetics of zidovudine, its glucuronide, and penicillin G via inhibition of UGT2B7 and/or OAT3.
Pulm Pharmacol Ther
; 72: 102097, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34800680
7.
Clinical disposition, metabolism and in vitro drug-drug interaction properties of omadacycline.
Xenobiotica
; 47(8): 682-696, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-27499331
8.
Evaluation of a potential transporter-mediated drug interaction between rosuvastatin and pradigastat, a novel DGAT-1 inhibitor.
Int J Clin Pharmacol Ther
; 53(5): 345-55, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25740267
9.
A plasma concentration of α-ketoglutarate influences the kinetic interaction of ligands with organic anion transporter 1.
Mol Pharmacol
; 86(1): 86-95, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24770989
10.
Variability in P-glycoprotein inhibitory potency (IC50) using various in vitro experimental systems: implications for universal digoxin drug-drug interaction risk assessment decision criteria.
Drug Metab Dispos
; 41(7): 1347-66, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23620485
11.
Application of receiver operating characteristic analysis to refine the prediction of potential digoxin drug interactions.
Drug Metab Dispos
; 41(7): 1367-74, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23620486
12.
Quantitation of UGT1A1 in human liver microsomes using stable isotope-labelled peptides and mass spectrometry based proteomic approaches.
Xenobiotica
; 43(4): 336-45, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22943130
13.
Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.
Eur J Clin Pharmacol
; 68(5): 697-708, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22124880
14.
Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective.
Clin Pharmacol Ther
; 112(3): 573-592, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35612761
15.
Predicting Oral Absorption for Compounds Outside the Rule of Five Property Space.
J Pharm Sci
; 110(6): 2562-2569, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33539870
16.
Genetic Diversity in Drug Transporters: Impact in African Populations.
Clin Transl Sci
; 13(5): 848-860, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32100958
17.
Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium.
Clin Pharmacol Ther
; 104(5): 836-864, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30347454
18.
Evaluation of Drug-Drug Interaction Potential Between Sacubitril/Valsartan (LCZ696) and Statins Using a Physiologically Based Pharmacokinetic Model.
J Pharm Sci
; 106(5): 1439-1451, 2017 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28089685
19.
Assessment of pharmacokinetic drug-drug interaction between pradigastat and atazanavir or probenecid.
J Clin Pharmacol
; 56(3): 355-64, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26189431
20.
Physiologically based pharmacokinetic modeling for assessing the clinical drug-drug interaction of alisporivir.
Eur J Pharm Sci
; 63: 103-12, 2014 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25008118