Detalles de la búsqueda
1.
Synthesis of fluorescent 5-heteroarylpyrimidine-containing oligonucleotides via post-synthetic trifluoromethyl conversion.
Org Biomol Chem
; 22(17): 3510-3517, 2024 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38619422
2.
Expansion of Phosphoramidite Chemistry in Solid-Phase Oligonucleotide Synthesis: Rapid 3'-Dephosphorylation and Strand Cleavage.
J Org Chem
; 88(5): 2726-2734, 2023 03 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36812161
3.
Synthesis of purine derivatives of Me-TaNA and properties of Me-TaNA-modified oligonucleotides.
Org Biomol Chem
; 21(25): 5203-5213, 2023 06 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37309204
4.
Synthesis of Nucleobase-Modified Oligonucleotides by Post-Synthetic Modification in Solution.
Chem Rec
; 22(5): e202100325, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35119181
5.
Synthesis and Properties of Oligonucleotides Containing 2'-O,4'-C-Methyleneoxy-Bridged Pyrimidine Derivatives.
J Org Chem
; 87(17): 11743-11750, 2022 09 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35960869
6.
2',4'-BNA/LNA with 9-(2-Aminoethoxy)-1,3-diaza-2-oxophenoxazine Efficiently Forms Duplexes and Has Enhanced Enzymatic Resistance*.
Chemistry
; 27(7): 2427-2438, 2021 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33280173
7.
Synthesis and properties of oligonucleotides bearing thymidine derivatives with 1,6-dioxaspiro[4.5]decane skeleton.
Bioorg Med Chem
; 31: 115966, 2021 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33387694
8.
Synthesis of Oligonucleotides Containing 2'-N-alkylaminocarbonyl-2'-amino-LNA (2'-urea-LNA) Moieties Using Post-Synthetic Modification Strategy.
Molecules
; 25(2)2020 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31952133
9.
Synthesis of the Methyl Analog of 2'-O,4'-C-Ethylene-Bridged 5-Methyluridine via Intramolecular Radical Cyclization and Properties of Modified Oligonucleotides.
J Org Chem
; 84(14): 9093-9100, 2019 07 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31241329
10.
Synthesis of 2'-C,4'-C-Methyleneoxy-Bridged Thymidine Derivatives and Properties of Modified Oligonucleotides.
J Org Chem
; 84(21): 13336-13344, 2019 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31565938
11.
Effective syntheses of 2',4'-BNANC monomers bearing adenine, guanine, thymine, and 5-methylcytosine, and the properties of oligonucleotides fully modified with 2',4'-BNANC.
Bioorg Med Chem
; 27(8): 1728-1741, 2019 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30862430
12.
Photoredox-Catalyzed Deformylative 1,4-Addition of 2'-Deoxy-5'- O-phthalimidonucleosides for Synthesis of 5'-Carba Analogs of Nucleoside 5'-Phosphates.
J Org Chem
; 83(18): 10701-10708, 2018 09 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-30136574
13.
Synthesis and hybridizing properties of isoDNAs including 3'-O,4'-C-ethyleneoxy-bridged 5-methyluridine derivatives.
Bioorg Med Chem
; 26(14): 3875-3881, 2018 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29861173
14.
Triazole- and Tetrazole-Bridged Nucleic Acids: Synthesis, Duplex Stability, Nuclease Resistance, and in Vitro and in Vivo Antisense Potency.
J Org Chem
; 82(1): 12-24, 2017 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27936689
15.
Synthesis and thermal stabilities of oligonucleotides containing 2'-O,4'-C-methylene bridged nucleic acid with a phenoxazine base.
Org Biomol Chem
; 15(38): 8145-8152, 2017 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28920119
16.
Synthesis, duplex-forming ability, enzymatic stability, and in vitro antisense potency of oligonucleotides including 2'-C,4'-C-ethyleneoxy-bridged thymidine derivatives.
Org Biomol Chem
; 15(18): 3955-3963, 2017 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28440828
17.
Triplex- and Duplex-Forming Abilities of Oligonucleotides Containing 2'-Deoxy-5-trifluoromethyluridine and 2'-Deoxy-5-trifluoromethylcytidine.
Chem Pharm Bull (Tokyo)
; 65(10): 982-988, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28966282
18.
Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.
Amino Acids
; 48(4): 1045-1058, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26724922
19.
Synthesis and properties of novel 2'-C,4'-C-ethyleneoxy-bridged 2'-deoxyribonucleic acids with exocyclic methylene groups.
Org Biomol Chem
; 14(40): 9481-9484, 2016 Oct 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27714307
20.
Effect of an N-substituent in sulfonamide-bridged nucleic acid (SuNA) on hybridization ability and duplex structure.
Org Biomol Chem
; 14(27): 6531-8, 2016 Jul 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27296230