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1.
Methodological considerations for measuring biofluid-based microRNA biomarkers.
Crit Rev Toxicol
; 51(3): 264-282, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34038674
2.
RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs for discerning baseline expression exclusivity of candidate biomarkers.
RNA Biol
; 17(5): 630-636, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32009518
3.
A cross-sector call to improve carcinogenicity risk assessment through use of genomic methodologies.
Regul Toxicol Pharmacol
; 110: 104526, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31726190
4.
A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.
PLoS Genet
; 11(2): e1004850, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25679959
5.
A Synopsis of the "Influence of Epigenetics, Genetics, and Immunology" Session Part A at the 35th Annual Society of Toxicologic Pathology Symposium.
Toxicol Pathol
; 45(1): 114-118, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27708198
6.
Green tea epigallocatechin gallate binds to and inhibits respiratory complexes in swelling but not normal rat hepatic mitochondria.
Biochem Biophys Res Commun
; 443(3): 1097-104, 2014 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24384371
7.
Dysregulation of protein degradation pathways may mediate the liver injury and phospholipidosis associated with a cationic amphiphilic antibiotic drug.
Toxicol Appl Pharmacol
; 280(1): 21-9, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24967691
8.
Liver biomarker and in vitro assessment confirm the hepatic origin of aminotransferase elevations lacking histopathological correlate in beagle dogs treated with GABAA receptor antagonist NP260.
Toxicol Appl Pharmacol
; 277(2): 131-7, 2014 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24699182
9.
Keratin-18 and microRNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts.
Liver Int
; 34(3): 367-78, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24118944
10.
Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans.
Genome Res
; 19(9): 1507-15, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19416960
11.
An analysis of N-acetylcysteine treatment for acetaminophen overdose using a systems model of drug-induced liver injury.
J Pharmacol Exp Ther
; 342(2): 529-40, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22593093
12.
In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI.
J Pharmacokinet Pharmacodyn
; 39(5): 527-41, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22875368
13.
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.
Toxicol Sci
; 188(1): 4-16, 2022 06 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35404422
14.
Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron.
Toxicol Sci
; 180(1): 1-16, 2021 02 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-33367795
15.
Urinary MicroRNAs in Environmental Health: Biomarkers of Emergent Kidney Injury and Disease.
Curr Environ Health Rep
; 7(2): 101-108, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32166731
16.
Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice.
Toxicol Sci
; 175(2): 220-235, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32170957
17.
Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency.
Cell Stem Cell
; 27(3): 459-469.e8, 2020 09 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32795400
18.
Replication and narrowing of gene expression quantitative trait loci using inbred mice.
Mamm Genome
; 20(7): 437-46, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19609828
19.
Mouse population-based evaluation of urinary protein and miRNA biomarker performance associated with cisplatin renal injury.
Exp Biol Med (Maywood)
; 243(3): 237-247, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29110506
20.
New Rodent Population Models May Inform Human Health Risk Assessment and Identification of Genetic Susceptibility to Environmental Exposures.
Environ Health Perspect
; 125(8): 086002, 2017 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28886592