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1.
Aminopyrazolo[1,5-a]pyrimidines as potential inhibitors of Mycobacterium tuberculosis: Structure activity relationships and ADME characterization.
Bioorg Med Chem
; 23(22): 7240-50, 2015 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26522089
2.
Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model.
J Med Chem
; 63(13): 6784-6801, 2020 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32433887
3.
How large does a compound screening collection need to be?
Comb Chem High Throughput Screen
; 11(6): 482-93, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18673276
4.
Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies.
J Med Chem
; 60(24): 10118-10134, 2017 12 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-29148755
5.
Chemogenomics: structuring the drug discovery process to gene families.
Drug Discov Today
; 11(19-20): 880-8, 2006 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16997137
6.
Bringing kinases into focus: efficient drug design through the use of chemogenomic toolkits.
Curr Med Chem
; 13(15): 1735-48, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-16787217
7.
Strategies for small molecule library design.
Curr Pharm Des
; 20(20): 3314-22, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-23947648
8.
Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) as an antiinflammatory target: discovery and in vivo activity of selective pyrazolo[1,5-a]pyrimidine inhibitors using a focused library and structure-based optimization approach.
J Med Chem
; 55(15): 6700-15, 2012 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-22746295
9.
The design and application of target-focused compound libraries.
Comb Chem High Throughput Screen
; 14(6): 521-31, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21521154
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