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1.
Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models.
Bioorg Med Chem Lett
; 29(1): 115-118, 2019 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30442420
2.
Optimization of an azetidine series as inhibitors of colony stimulating factor-1 receptor (CSF-1R) Type II to lead to the clinical candidate JTE-952.
Bioorg Med Chem Lett
; 29(7): 873-877, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30755337
3.
New aminopropandiol derivatives as orally available and short-acting calcium-sensing receptor antagonists.
Bioorg Med Chem Lett
; 20(12): 3809-13, 2010 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20472433
4.
Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders.
J Med Chem
; 63(13): 7163-7185, 2020 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32511913
5.
Discovery of Second Generation RORγ Inhibitors Composed of an Azole Scaffold.
J Med Chem
; 62(5): 2837-2842, 2019 03 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30776227
6.
Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109.
J Med Chem
; 49(15): 4721-36, 2006 Jul 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-16854079
7.
Discovery of conformationally constrained tetracyclic compounds as potent hepatitis C virus NS5B RNA polymerase inhibitors.
J Med Chem
; 49(24): 6950-3, 2006 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-17125247
8.
SAR Exploration Guided by LE and Fsp(3): Discovery of a Selective and Orally Efficacious RORγ Inhibitor.
ACS Med Chem Lett
; 7(1): 23-7, 2016 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26819660
9.
4-(4-cycloalkyl/aryl-oxazol-5-yl)benzenesulfonamides as selective cyclooxygenase-2 inhibitors: enhancement of the selectivity by introduction of a fluorine atom and identification of a potent, highly selective, and orally active COX-2 inhibitor JTE-522(1).
J Med Chem
; 45(7): 1511-7, 2002 Mar 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-11906292
10.
Discovery of a potent and short-acting oral calcilytic with a pulsatile secretion of parathyroid hormone.
ACS Med Chem Lett
; 2(3): 238-42, 2011 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900301
11.
Further studies on hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors toward improved replicon cell activities: benzimidazole and structurally related compounds bearing the 2-morpholinophenyl moiety.
Bioorg Med Chem Lett
; 17(11): 3181-6, 2007 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17383878
12.
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole.
Bioorg Med Chem Lett
; 16(7): 1859-63, 2006 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16455252
13.
4-Aryl/cycloalkyl-5-phenyloxazole derivatives as selective COX-2 inhibitors.
Bioorg Med Chem Lett
; 12(1): 65-8, 2002 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-11738574
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