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1.
Inhibitory Roles of Apolipoprotein E Christchurch Astrocytes in Curbing Tau Propagation Using Human Pluripotent Stem Cell-Derived Models.
J Neurosci
; 44(24)2024 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38649269
2.
Casein kinase 1δ/ε phosphorylates fused in sarcoma (FUS) and ameliorates FUS-mediated neurodegeneration.
J Biol Chem
; 298(8): 102191, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35753345
3.
ALS-linked cytoplasmic FUS assemblies are compositionally different from physiological stress granules and sequester hnRNPA3, a novel modifier of FUS toxicity.
Neurobiol Dis
; 162: 105585, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34915152
4.
Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.
PLoS Genet
; 15(8): e1008308, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31390360
5.
Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy.
RNA Biol
; 18(11): 1546-1554, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33427561
6.
Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration.
Hum Mol Genet
; 27(8): 1353-1365, 2018 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29425337
7.
Neuron-specific methylome analysis reveals epigenetic regulation and tau-related dysfunction of BRCA1 in Alzheimer's disease.
Proc Natl Acad Sci U S A
; 114(45): E9645-E9654, 2017 11 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29042514
8.
Patterns and severity of vascular amyloid in Alzheimer's disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer's disease.
Acta Neuropathol
; 136(4): 569-587, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29770843
9.
Familial Amyotrophic Lateral Sclerosis-linked Mutations in Profilin 1 Exacerbate TDP-43-induced Degeneration in the Retina of Drosophila melanogaster through an Increase in the Cytoplasmic Localization of TDP-43.
J Biol Chem
; 291(45): 23464-23476, 2016 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27634045
10.
Role of Apolipoprotein E in ß-Amyloidogenesis: ISOFORM-SPECIFIC EFFECTS ON PROTOFIBRIL TO FIBRIL CONVERSION OF Aß IN VITRO AND BRAIN Aß DEPOSITION IN VIVO.
J Biol Chem
; 290(24): 15163-74, 2015 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-25918154
11.
CLAC-P/collagen type XXV is required for the intramuscular innervation of motoneurons during neuromuscular development.
J Neurosci
; 34(4): 1370-9, 2014 Jan 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-24453327
12.
RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy.
Hum Mol Genet
; 22(22): 4474-84, 2013 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23804749
13.
Role of apolipoprotein E in ß-amyloidogenesis: Isoform-specific effects on protofibril to fibril conversion of Aß in vitro and brain Aß deposition in vivo.
J Biol Chem
; 293(19): 7267, 2018 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29752420
14.
Brain interstitial oligomeric amyloid ß increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease.
FASEB J
; 27(8): 3239-48, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23640054
15.
Distinct dendritic spine and nuclear phases of calcineurin activation after exposure to amyloid-ß revealed by a novel fluorescence resonance energy transfer assay.
J Neurosci
; 32(15): 5298-309, 2012 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-22496575
16.
Inhibition of the NFAT pathway alleviates amyloid ß neurotoxicity in a mouse model of Alzheimer's disease.
J Neurosci
; 32(9): 3176-92, 2012 Feb 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-22378890
17.
Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid ß peptide.
J Neurosci
; 32(43): 15181-92, 2012 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-23100439
18.
Identification of small molecule inhibitors of neurite loss induced by Aß peptide using high content screening.
J Biol Chem
; 287(12): 8714-23, 2012 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-22277654
19.
Neuronal activity and secreted amyloid ß lead to altered amyloid ß precursor protein and presenilin 1 interactions.
Neurobiol Dis
; 50: 127-34, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23064434
20.
The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system.
Am J Pathol
; 181(4): 1426-35, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22867711