Detalles de la búsqueda
1.
Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA.2.
Nature
; 607(7917): 119-127, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35576972
2.
Characterization of a new SARS-CoV-2 variant that emerged in Brazil.
Proc Natl Acad Sci U S A
; 118(27)2021 07 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34140350
3.
SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads.
Bioorg Med Chem Lett
; 96: 129489, 2023 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37770002
4.
Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development.
Proc Natl Acad Sci U S A
; 117(28): 16587-16595, 2020 07 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32571934
5.
Exploratory Studies of Effective Inhibitors against the SARS-CoV-2 Main Protease by Halogen Incorporation and Amide Bond Replacement.
Chem Pharm Bull (Tokyo)
; 71(12): 879-886, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38044140
6.
Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations.
J Virol
; 95(16): e0240120, 2021 07 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-34076480
7.
Neutralising activity and antibody titre in 10 patients with breakthrough infections of the SARS-CoV-2 Omicron variant in Japan.
J Infect Chemother
; 28(9): 1340-1343, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-35644734
8.
Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV.
J Hepatol
; 74(5): 1075-1086, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33333207
9.
Chloropyridinyl Esters of Nonsteroidal Anti-Inflammatory Agents and Related Derivatives as Potent SARS-CoV-2 3CL Protease Inhibitors.
Molecules
; 26(19)2021 Sep 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34641337
10.
Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C-induced HIV latency reversal.
J Biol Chem
; 294(1): 116-129, 2019 01 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30413535
11.
Correction for Nakajima et al., "Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations".
J Virol
; 98(3): e0182323, 2024 Mar 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38305151
12.
Halogen Bond Interactions of Novel HIV-1 Protease Inhibitors (PI) (GRL-001-15 and GRL-003-15) with the Flap of Protease Are Critical for Their Potent Activity against Wild-Type HIV-1 and Multi-PI-Resistant Variants.
Antimicrob Agents Chemother
; 63(6)2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-30962341
13.
CMCdG, a Novel Nucleoside Analog with Favorable Safety Features, Exerts Potent Activity against Wild-Type and Entecavir-Resistant Hepatitis B Virus.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30670420
14.
Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors.
Biochem Biophys Res Commun
; 509(4): 943-948, 2019 02 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-30648556
15.
Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation.
Bioorg Med Chem Lett
; 29(18): 2565-2570, 2019 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31416666
16.
GRL-079, a Novel HIV-1 Protease Inhibitor, Is Extremely Potent against Multidrug-Resistant HIV-1 Variants and Has a High Genetic Barrier against the Emergence of Resistant Variants.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29463535
17.
Transmission of SARS-CoV-2 in Domestic Cats.
N Engl J Med
; 383(6): 592-594, 2020 08 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32402157
18.
Exploration of P1 and P4 modifications of nirmatrelvir: Design, synthesis, biological evaluation, and X-ray structural studies of SARS-CoV-2 Mpro inhibitors.
Eur J Med Chem
; 267: 116132, 2024 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38335815
19.
Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation.
Eur J Med Chem
; 255: 115385, 2023 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37150084
20.
Structure-Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2-carbonyl Moieties.
J Med Chem
; 66(19): 13516-13529, 2023 Oct 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37756225