Detalles de la búsqueda
1.
Self-immolative polycations as gene delivery vectors and prodrugs targeting polyamine metabolism in cancer.
Mol Pharm
; 12(2): 332-41, 2015 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25153488
2.
Alternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway in human gut microbiota.
J Biol Chem
; 286(50): 43301-12, 2011 Dec 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-22025614
3.
Cyclam-based polymeric copper chelators for gene delivery and potential PET imaging.
Biomacromolecules
; 13(10): 3220-7, 2012 Oct 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-23004346
4.
Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol: identification of highly potent and selective agonists for dopamine D3 receptor with potent in vivo activity.
J Med Chem
; 51(10): 3005-19, 2008 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-18410082
5.
The role of autophagy in the death of L1210 leukemia cells initiated by the new antitumor agents, XK469 and SH80.
Mol Cancer Ther
; 6(1): 370-9, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17237296
6.
Dual-function CXCR4 antagonist polyplexes to deliver gene therapy and inhibit cancer cell invasion.
Angew Chem Int Ed Engl
; 51(35): 8740-3, 2012 Aug 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-22855422
7.
Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters.
J Med Chem
; 49(14): 4239-47, 2006 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-16821783
8.
Development of functional poly(amido amine) CXCR4 antagonists with the ability to mobilize leukocytes and deliver nucleic acids.
Adv Healthc Mater
; 4(5): 729-38, 2015 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25491178
9.
II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).
J Med Chem
; 45(14): 3130-7, 2002 Jul 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-12086498
10.
Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1.
J Med Chem
; 55(17): 7378-91, 2012 Sep 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-22876979
11.
Polyamine-based small molecule epigenetic modulators.
Medchemcomm
; 3(1): 14-21, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23293738
12.
Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.
J Med Chem
; 54(8): 2924-32, 2011 Apr 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-21446715
13.
Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5.
Bioorg Med Chem
; 14(7): 2462-7, 2006 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16337128
14.
Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4.
Bioorg Med Chem
; 13(12): 3910-20, 2005 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-15911307
15.
Part 3: synthesis and biological evaluation of some analogs of the antitumor agents, 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid, and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid.
Bioorg Med Chem
; 13(4): 1069-81, 2005 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15670915
16.
Lack of in vitro-in vivo correlation of a novel investigational anticancer agent, SH 30.
Invest New Drugs
; 20(1): 23-33, 2002 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12003192
17.
Preclinical efficacy evaluations of XK-469: dose schedule, route and cross-resistance behavior in tumor bearing mice.
Invest New Drugs
; 20(1): 13-22, 2002 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-12003190
Resultados
1 -
17
de 17
1
Próxima >
>>