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1.
The effect of mild to moderate renal impairment on the pharmacokinetics of the nucleoside analog hepatitis C virus polymerase inhibitor mericitabine.
Drug Dev Res
; 75(2): 107-13, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24648253
2.
SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity.
Mol Cancer Ther
; 5(7): 1774-82, 2006 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-16891463
3.
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.
Clin Cancer Res
; 9(1): 327-37, 2003 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12538485
4.
Single-dose pharmacokinetics of the HCV polymerase inhibitor mericitabine in healthy Caucasian and Japanese subjects.
Drug Metab Pharmacokinet
; 29(2): 141-7, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24025983
5.
Evaluation of the effect of mericitabine at projected therapeutic and supratherapeutic doses on cardiac repolarization in healthy subjects: A thorough QT/QTc study.
Clin Pharmacol Drug Dev
; 3(3): 179-86, 2014 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27128607
6.
Identification of longitudinally dynamic biomarkers in Alzheimer's disease cerebrospinal fluid by targeted proteomics.
Mol Neurodegener
; 9: 22, 2014 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-24902845
7.
Impact of low-dose ritonavir on danoprevir pharmacokinetics: results of computer-based simulations and a clinical drug-drug interaction study.
Clin Pharmacokinet
; 51(7): 457-65, 2012 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22624502
8.
Synthesis and in Vitro and in Vivo Evaluation of Phosphoinositide-3-kinase Inhibitors.
ACS Med Chem Lett
; 2(1): 34-8, 2011 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900252
9.
Identification of NVP-BKM120 as a Potent, Selective, Orally Bioavailable Class I PI3 Kinase Inhibitor for Treating Cancer.
ACS Med Chem Lett
; 2(10): 774-9, 2011 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900266
10.
Single- and multiple-dose disposition kinetics of sunitinib malate, a multitargeted receptor tyrosine kinase inhibitor: comparative plasma kinetics in non-clinical species.
Cancer Chemother Pharmacol
; 64(4): 691-706, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19169880
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