Detalles de la búsqueda
1.
Rare oncology therapeutics: review of clinical pharmacology package of drug approvals (2019-2023) by US FDA, best practices and recommendations.
J Pharmacokinet Pharmacodyn
; 50(6): 475-493, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37925369
2.
Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.
Clin Immunol
; 191: 10-20, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29518577
3.
Exposure-response characterization of tofacitinib efficacy in moderate to severe ulcerative colitis: Results from a dose-ranging phase 2 trial.
Br J Clin Pharmacol
; 84(6): 1136-1145, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29377257
4.
Tofacitinib pharmacokinetics in children and adolescents with juvenile idiopathic arthritis.
CPT Pharmacometrics Syst Pharmacol
; 13(4): 599-611, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38298058
5.
Demonstrating Bioequivalence for Two Dose Strengths of Niraparib and Abiraterone Acetate Dual-Action Tablets Versus Single Agents: Utility of Clinical Study Data Supplemented with Modeling and Simulation.
Clin Pharmacokinet
; 63(4): 511-527, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38436924
6.
Subcutaneous Administration of Monoclonal Antibodies: Pharmacology, Delivery, Immunogenicity, and Learnings From Applications to Clinical Development.
Clin Pharmacol Ther
; 115(3): 422-439, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38093583
7.
Linvoseltamab for Treatment of Relapsed/Refractory Multiple Myeloma.
J Clin Oncol
; : JCO2401008, 2024 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-38879802
8.
First-in-human, open-label, phase 1/2 study of the monoclonal antibody programmed cell death protein-1 (PD-1) inhibitor cetrelimab (JNJ-63723283) in patients with advanced cancers.
Cancer Chemother Pharmacol
; 89(4): 499-514, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35298698
9.
Pharmacokinetics and Use-Testing of Apalutamide Prepared in Aqueous Food Vehicles for Alternative Administration.
Clin Pharmacol Drug Dev
; 10(11): 1375-1384, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34273257
10.
Translational PK/PD and model-informed development of JNJ-67842125, a Fab reversal agent for JNJ-64179375, a long-acting thrombin inhibitor.
Br J Pharmacol
; 178(19): 3943-3958, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34008170
11.
Niraparib with androgen receptor-axis-targeted therapy in patients with metastatic castration-resistant prostate cancer: safety and pharmacokinetic results from a phase 1b study (BEDIVERE).
Cancer Chemother Pharmacol
; 88(1): 25-37, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33754187
12.
Evaluation of the Short-, Mid-, and Long-Term Effects of Tofacitinib on Lymphocytes in Patients With Rheumatoid Arthritis.
Arthritis Rheumatol
; 71(5): 685-695, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30427585
13.
Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study.
Pediatr Rheumatol Online J
; 15(1): 86, 2017 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-29282090
14.
Emerging areas of research in the assessment of pharmacokinetics in patients with chronic kidney disease.
J Clin Pharmacol
; 55(3): 241-50, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-25501531
15.
Estimating vapor pressure curves by thermogravimetry: a rapid and convenient method for characterization of pharmaceuticals.
Eur J Pharm Biopharm
; 54(2): 171-80, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12191689
16.
An evaporation study for phthalic acids--a rapid method for pharmaceutical characterization.
J Pharm Sci
; 91(4): 1156-68, 2002 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-11948554
17.
Pharmacodynamic modeling of acute and chronic effects of methylprednisolone on hepatic urea cycle genes in rats.
Gene Regul Syst Bio
; 2: 1-19, 2008 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-19787073
18.
Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats.
Pharm Res
; 25(4): 769-80, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17674160
19.
Pharmacokinetics of methylprednisolone after intravenous and intramuscular administration in rats.
Biopharm Drug Dispos
; 28(6): 263-73, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17569107
20.
Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids.
J Pharmacokinet Pharmacodyn
; 34(5): 643-67, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17593325