Detalles de la búsqueda
1.
Resistance and cross-resistance profile of the diaryltriazine NNRTI and candidate microbicide UAMC01398.
J Antimicrob Chemother
; 71(5): 1159-68, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26850721
2.
From human immunodeficiency virus non-nucleoside reverse transcriptase inhibitors to potent and selective antitrypanosomal compounds.
Bioorg Med Chem
; 22(19): 5241-8, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25199582
3.
Diaryltriazine non-nucleoside reverse transcriptase inhibitors are potent candidates for pre-exposure prophylaxis in the prevention of sexual HIV transmission.
J Antimicrob Chemother
; 68(9): 2038-47, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23645585
4.
Synthesis, evaluation and structure-activity relationships of triazine dimers as novel antiviral agents.
Bioorg Med Chem Lett
; 22(23): 7174-8, 2012 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23084903
5.
Novel diarylpyridinones, diarylpyridazinones and diarylphthalazinones as potential HIV-1 nonnucleoside reverse transcriptase inhibitors (NNRTIs).
Bioorg Med Chem
; 19(20): 5924-34, 2011 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21930388
6.
7.
Novel triazine dimers with potent antitrypanosomal activity.
Eur J Med Chem
; 143: 306-319, 2018 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29197735
8.
Synthesis of novel diarylpyrimidine analogues of TMC278 and their antiviral activity against HIV-1 wild-type and mutant strains.
Eur J Med Chem
; 42(5): 567-79, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17223230
9.
2,6-Di(arylamino)-3-fluoropyridine Derivatives as HIV Non-Nucleoside Reverse Transcriptase Inhibitors.
J Med Chem
; 59(5): 1854-68, 2016 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26785139
10.
Structure based activity prediction of HIV-1 reverse transcriptase inhibitors.
J Med Chem
; 48(6): 2176-83, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771460
11.
In search of a novel anti-HIV drug: multidisciplinary coordination in the discovery of 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-2- pyrimidinyl]amino]benzonitrile (R278474, rilpivirine).
J Med Chem
; 48(6): 1901-9, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771434
12.
Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity.
J Med Chem
; 48(6): 1910-8, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771435
13.
Synthesis of novel diarylpyrimidine analogues and their antiviral activity against human immunodeficiency virus type 1.
J Med Chem
; 48(6): 2072-9, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771449
14.
Synthesis and in vitro and in vivo structure-activity relationships of novel antifungal triazoles for dermatology.
J Med Chem
; 48(6): 2184-93, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771461
15.
A pharmacophore docking algorithm and its application to the cross-docking of 18 HIV-NNRTI's in their binding pockets.
Proteins
; 54(3): 526-33, 2004 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14748000
16.
SYNOPSIS: SYNthesize and OPtimize System in Silico.
J Med Chem
; 46(13): 2765-73, 2003 Jun 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-12801239
17.
Roles of conformational and positional adaptability in structure-based design of TMC125-R165335 (etravirine) and related non-nucleoside reverse transcriptase inhibitors that are highly potent and effective against wild-type and drug-resistant HIV-1 variants.
J Med Chem
; 47(10): 2550-60, 2004 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-15115397
18.
Correlations between factors determining the pharmacokinetics and antiviral activity of HIV-1 non-nucleoside reverse transcriptase inhibitors of the diaryltriazine and diarylpyrimidine classes of compounds.
Drugs R D
; 5(5): 245-57, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15357624
19.
Development and in vitro evaluation of a vaginal microbicide gel formulation for UAMC01398, a novel diaryltriazine NNRTI against HIV-1.
Antiviral Res
; 101: 113-21, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24269474
20.
Reverse transcriptase inhibitors as microbicides.
Curr HIV Res
; 10(1): 27-35, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22264043