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1.

Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive rats.

Linz, W; Heitsch, H; Schölkens, B A; Wiemer, G.

Hypertension ; 35(4): 908-13, 2000 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-10775560

2.

Non-peptide antagonists and agonists of the bradykinin B(2) receptor.

Heitsch, H.

Curr Med Chem ; 9(9): 913-28, 2002 May.

Artículo en Inglés | MEDLINE | ID: mdl-11966453

3.

Cardioselective K(ATP) channel blockers derived from a new series of m-anisamidoethylbenzenesulfonylthioureas.

Englert, H C; Gerlach, U; Goegelein, H; Hartung, J; Heitsch, H; Mania, D; Scheidler, S.

J Med Chem ; 44(7): 1085-98, 2001 Mar 29.

Artículo en Inglés | MEDLINE | ID: mdl-11297455

4.

Renin inhibitors containing a pyridyl amino diol derived C-terminus.

Heitsch, H; Henning, R; Kleemann, H W; Linz, W; Nickel, W U; Ruppert, D; Urbach, H; Wagner, A.

J Med Chem ; 36(19): 2788-800, 1993 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-8410992

5.

Sulfonylureas and sulfonylcarbamates as new non-tetrazole angiotensin II receptor antagonists. Discovery of a highly potent orally active (imidazolylbiphenylyl)sulfonylurea (HR 720).

Deprez, P; Guillaume, J; Becker, R; Corbier, A; Didierlaurent, S; Fortin, M; Frechet, D; Hamon, G; Heckmann, B; Heitsch, H.

J Med Chem ; 38(13): 2357-77, 1995 Jun 23.

Artículo en Inglés | MEDLINE | ID: mdl-7608902

6.

Renin inhibitory pentols showing improved enteral bioavailability.

Kleemann, H W; Heitsch, H; Henning, R; Kramer, W; Kocher, W; Lerch, U; Linz, W; Nickel, W U; Ruppert, D; Urbach, H.

J Med Chem ; 35(3): 559-67, 1992 Feb 07.

Artículo en Inglés | MEDLINE | ID: mdl-1738148

7.

Bradykinin B2 receptor as a potential therapeutic target.

Heitsch, H.

Drug News Perspect ; 13(4): 213-25, 2000 May.

Artículo en Inglés | MEDLINE | ID: mdl-12937626

8.

Amyloid beta-(1-40) stimulates cyclic GMP production via release of kinins in primary cultured endothelial cells.

Wirth, K J; Fink, E; Rudolphi, K; Heitsch, H; Deutschländer, N; Wiemer, G.

Eur J Pharmacol ; 382(1): 27-33, 1999 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-10556501

9.

The bradykinin B2 receptor antagonist Icatibant (HOE 140) corrects avid Na+ retention in rats with CCl4-induced liver cirrhosis: possible role of enhanced microvascular leakage.

Wirth, K J; Bickel, M; Hropot, M; Günzler, V; Heitsch, H; Ruppert, D; Schölkens, B A.

Eur J Pharmacol ; 337(1): 45-53, 1997 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-9389380

10.

Bradykinin receptor antagonists.

Heitsch, H.

IDrugs ; 2(6): 567-75, 1999 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-16127619

11.

Metabolic products of microorganisms. 255. Nikkomycins Wz and Wx, new chitin synthetase inhibitors from Streptomyces tendae.

Decker, H; Walz, F; Bormann, C; Zähner, H; Fiedler, H P; Heitsch, H; König, W A.

J Antibiot (Tokyo) ; 43(1): 43-8, 1990 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-2137814

12.

Metabolic products of microorganisms. 254. Structure of the new nikkomycins pseudo-Z and pseudo-J.

Heitsch, H; König, W A; Decker, H; Bormann, C; Fiedler, H P; Zähner, H.

J Antibiot (Tokyo) ; 42(5): 711-7, 1989 May.

Artículo en Inglés | MEDLINE | ID: mdl-2722685

13.

Metabolic products of microorganisms. 252. Isolation of new nikkomycins from Streptomyces tendae.

Decker, H; Bormann, C; Fiedler, H P; Zähner, H; Heitsch, H; König, W A.

J Antibiot (Tokyo) ; 42(2): 230-5, 1989 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-2925514

14.

The possible role of angiotensin II subtype AT2 receptors in endothelial cells and isolated ischemic rat hearts.

Wiemer, G; Schölkens, B A; Wagner, A; Heitsch, H; Linz, W.

J Hypertens Suppl ; 11(5): S234-5, 1993 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-8158361

15.

Kinin receptor antagonists: unique probes in basic and clinical research.

Wirth, K J; Heitsch, H; Schölkens, B A.

Can J Physiol Pharmacol ; 73(7): 797-804, 1995 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-8846412

16.

Novel series of O-substituted 8-quinolines and 4-benzothiazoles as potent antagonists of the bradykinin B2 receptors.

Heitsch, H; Wagner, A; Schölkens, B A; Wirth, K.

Bioorg Med Chem Lett ; 9(3): 327-32, 1999 Feb 08.

Artículo en Inglés | MEDLINE | ID: mdl-10091678

17.

Structure-activity relationships of the nikkomycins.

Decker, H; Zähner, H; Heitsch, H; König, W A; Fiedler, H P.

J Gen Microbiol ; 137(8): 1805-13, 1991 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-1955867

18.

An investigation of the irritant and allergenic properties of daffodils (Narcissus pseudonarcissus L., Amaryllidaceae). A review of daffodil dermatitis.

Gude, M; Hausen, B M; Heitsch, H; König, W A.

Contact Dermatitis ; 19(1): 1-10, 1988 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-2972509

19.

3N-methylbiphenylsulfonylurea and -carbamate substituted imidazo[4,5-b]pyridines. Potent antagonists of the ANG II AT1 receptors.

Heitsch, H; Becker, R H; Kleemann, H W; Wagner, A.

Bioorg Med Chem ; 5(4): 673-8, 1997 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-9158865

20.

Structure-activity relationships in allergic contact dermatitis (I). Studies on the influence of side-chain length with derivatives of primin.

Hausen, B M; Heitsch, H; Borrmann, B; Koch, D; Rathmann, R; Richter, B; König, W A.

Contact Dermatitis ; 33(1): 12-6, 1995 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-7493455

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Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive rats.

Non-peptide antagonists and agonists of the bradykinin B(2) receptor.

Cardioselective K(ATP) channel blockers derived from a new series of m-anisamidoethylbenzenesulfonylthioureas.

Renin inhibitors containing a pyridyl amino diol derived C-terminus.

Sulfonylureas and sulfonylcarbamates as new non-tetrazole angiotensin II receptor antagonists. Discovery of a highly potent orally active (imidazolylbiphenylyl)sulfonylurea (HR 720).

Renin inhibitory pentols showing improved enteral bioavailability.

Bradykinin B2 receptor as a potential therapeutic target.

Amyloid beta-(1-40) stimulates cyclic GMP production via release of kinins in primary cultured endothelial cells.

The bradykinin B2 receptor antagonist Icatibant (HOE 140) corrects avid Na+ retention in rats with CCl4-induced liver cirrhosis: possible role of enhanced microvascular leakage.

Bradykinin receptor antagonists.

Metabolic products of microorganisms. 255. Nikkomycins Wz and Wx, new chitin synthetase inhibitors from Streptomyces tendae.

Metabolic products of microorganisms. 254. Structure of the new nikkomycins pseudo-Z and pseudo-J.

Metabolic products of microorganisms. 252. Isolation of new nikkomycins from Streptomyces tendae.

The possible role of angiotensin II subtype AT2 receptors in endothelial cells and isolated ischemic rat hearts.

Kinin receptor antagonists: unique probes in basic and clinical research.

Novel series of O-substituted 8-quinolines and 4-benzothiazoles as potent antagonists of the bradykinin B2 receptors.

Structure-activity relationships of the nikkomycins.

An investigation of the irritant and allergenic properties of daffodils (Narcissus pseudonarcissus L., Amaryllidaceae). A review of daffodil dermatitis.

3N-methylbiphenylsulfonylurea and -carbamate substituted imidazo[4,5-b]pyridines. Potent antagonists of the ANG II AT1 receptors.

Structure-activity relationships in allergic contact dermatitis (I). Studies on the influence of side-chain length with derivatives of primin.