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1.
Mutual Cooperativity of Three Allosteric Sites on the Dopamine D1 Receptor.
Mol Pharmacol
; 103(3): 176-187, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36804203
2.
Ensemble Docking Approach to Mitigate Pregnane X Receptor-Mediated CYP3A4 Induction Risk.
J Chem Inf Model
; 63(1): 173-186, 2023 01 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36473234
3.
Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints.
Bioorg Med Chem
; 28(1): 115194, 2020 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31786008
4.
The synthesis and evaluation of triazolopyrimidines as anti-tubercular agents.
Bioorg Med Chem
; 25(15): 3922-3946, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28576632
5.
Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug-Drug Interaction Risk Profile.
J Med Chem
; 65(5): 3786-3797, 2022 03 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35175768
6.
Novel Trifluoromethyl Pyrimidinone Compounds With Activity Against Mycobacterium tuberculosis.
Front Chem
; 9: 613349, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33996738
7.
Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor.
J Med Chem
; 64(12): 8076-8100, 2021 06 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34081466
8.
In Vitro and In Vivo Correlation of Hepatic Fraction of Metabolism by P450 in Dogs.
J Pharm Sci
; 108(2): 1017-1026, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30244007
9.
Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 Receptor.
J Med Chem
; 62(19): 8711-8732, 2019 10 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31532644
10.
3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism.
J Neurosci
; 27(10): 2718-26, 2007 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-17344409
11.
A Practical Synthesis of (-)-Swainsonine.
J Org Chem
; 61(20): 7217-7221, 1996 Oct 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-11667634
12.
An Asymmetric Synthesis of C-2-epi-Hygromycin A We thank the National Science Foundation and the National Institute of Health, General Medical Sciences, for their generous support of our programs. O.D. thanks the Association pour la Recherche contre le Cancer (ARC) for a postdoctoral fellowship. Mass spectra were kindly provided by the Mass Spectrometry Facility, University of San Francisco, supported by the NIH Division of Research Resources.
Angew Chem Int Ed Engl
; 40(19): 3658-3660, 2001 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-11592213
13.
Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond.
Alcohol
; 43(7): 491-8, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19913192
14.
A study of the synthesis of triazoles using microwave irradiation.
Mol Divers
; 7(2-4): 171-4, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-14870847
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