Detalles de la búsqueda
1.
Dose-response effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial.
Diabetologia
; 67(3): 470-482, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38095657
2.
Acylated- and unacylated ghrelin during an oral glucose tolerance test in humans at risk for type 2 diabetes mellitus.
Int J Obes (Lond)
; 47(9): 825-832, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37420007
3.
A randomized Phase I study of the safety, tolerability, pharmacokinetics and pharmacodynamics of BI 456906, a dual glucagon receptor/glucagon-like peptide-1 receptor agonist, in healthy Japanese men with overweight/obesity.
Diabetes Obes Metab
; 25(7): 1973-1984, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36974349
4.
Phase I studies of the safety, tolerability, pharmacokinetics and pharmacodynamics of the dual glucagon receptor/glucagon-like peptide-1 receptor agonist BI 456906.
Diabetes Obes Metab
; 25(4): 1011-1023, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36527386
5.
Correction to: Dose-response effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial.
Diabetologia
; 67(4): 758, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38349400
6.
Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ.
Diabetologia
; 58(12): 2819-31, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26363783
7.
Perspectives in weight control in diabetes - Survodutide.
Diabetes Res Clin Pract
; 207: 110779, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37330144
8.
Glucagon and GLP-1 receptor dual agonist survodutide for obesity: a randomised, double-blind, placebo-controlled, dose-finding phase 2 trial.
Lancet Diabetes Endocrinol
; 12(3): 162-173, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38330987
9.
Prevalence of Overweight and Obesity, Its Complications, and Progression in a 10-Year Follow-Up in the Gutenberg Health Study (GHS).
Obes Facts
; 17(1): 12-23, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-37839401
10.
Obesity-related inflammatory protein signature in cardiovascular clinical outcomes: results from the Gutenberg Health Study.
Obesity (Silver Spring)
; 2024 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38664310
11.
Toll-like receptors 2 and 4 impair insulin-mediated brain activity by interleukin-6 and osteopontin and alter sleep architecture.
FASEB J
; 26(5): 1799-809, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22278939
12.
Stratification of obesity phenotypes to optimize future therapy (SOPHIA).
Expert Rev Gastroenterol Hepatol
; 17(10): 1031-1039, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37791820
13.
Leptin affects insulin action in astrocytes and impairs insulin-mediated physical activity.
Cell Physiol Biochem
; 30(1): 238-46, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22759970
14.
Insulin-induced serine phosphorylation of IRS-2 via ERK1/2 and mTOR: studies on the function of Ser675 and Ser907.
Am J Physiol Endocrinol Metab
; 300(5): E824-36, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21098738
15.
Challenges in tackling energy expenditure as obesity therapy: From preclinical models to clinical application.
Mol Metab
; 51: 101237, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33878401
16.
Enforced expression of protein kinase C in skeletal muscle causes physical inactivity, fatty liver and insulin resistance in the brain.
J Cell Mol Med
; 14(4): 903-13, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20569275
17.
Acute regulation of metabolic genes and insulin receptor substrates in the liver of mice by one single bout of treadmill exercise.
J Physiol
; 587(1): 241-52, 2009 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19001047
18.
The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet.
J Clin Endocrinol Metab
; 104(6): 2041-2053, 2019 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30541128
19.
IGF-1 protects against dexamethasone-induced cell death in insulin secreting INS-1 cells independent of AKT/PKB phosphorylation.
Cell Physiol Biochem
; 21(5-6): 455-62, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-18453753
20.
Effect of insulin detemir, compared to human insulin, on 3T3-L1 adipogenesis.
Regul Pept
; 151(1-3): 160-3, 2008 Nov 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-18571747