Detalles de la búsqueda
1.
Highly Neutralizing COVID-19 Convalescent Plasmas Potently Block SARS-CoV-2 Replication and Pneumonia in Syrian Hamsters.
J Virol
; 96(4): e0155121, 2022 02 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-34818068
2.
SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads.
Bioorg Med Chem Lett
; 96: 129489, 2023 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37770002
3.
Exploratory Studies of Effective Inhibitors against the SARS-CoV-2 Main Protease by Halogen Incorporation and Amide Bond Replacement.
Chem Pharm Bull (Tokyo)
; 71(12): 879-886, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38044140
4.
Effects of a novel hepatitis B anti-viral drug E-CFCP in renal organic acid transporters.
J Pharmacol Sci
; 150(4): 201-203, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36344041
5.
Identification of a novel long-acting 4'-modified nucleoside reverse transcriptase inhibitor against HBV.
J Hepatol
; 74(5): 1075-1086, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33333207
6.
CMCdG, a Novel Nucleoside Analog with Favorable Safety Features, Exerts Potent Activity against Wild-Type and Entecavir-Resistant Hepatitis B Virus.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30670420
7.
Restoration of Neutralization Activity Against Omicron BA.2 and BA.5 in Older Adults and Individuals With Risk Factors Following the Fourth Dose of Severe Acute Respiratory Syndrome Coronavirus 2 BNT162b2 Vaccine.
J Infect Dis
; 227(1): 161-163, 2022 12 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-36134611
8.
4'-modified nucleoside analogs: potent inhibitors active against entecavir-resistant hepatitis B virus.
Hepatology
; 62(4): 1024-36, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26122273
9.
Exploration of P1 and P4 modifications of nirmatrelvir: Design, synthesis, biological evaluation, and X-ray structural studies of SARS-CoV-2 Mpro inhibitors.
Eur J Med Chem
; 267: 116132, 2024 Mar 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38335815
10.
A lipid index for risk of hyperlipidemia caused by anti-retroviral drugs.
Antiviral Res
; 223: 105819, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38272319
11.
A novel anti-HBV agent, E-CFCP, restores Hepatitis B virus (HBV)-induced senescence-associated cellular marker perturbation in human hepatocytes.
Virus Res
; 329: 199094, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36933835
12.
Neutralization against Omicron sublineages (BA.2/BA.5/BQ.1.1/XBB/XBB.1.5) in bivalent BNT162b2-vaccinated HCWs with or without risk factors, or following BT infection with Omicron.
Sci Rep
; 13(1): 17404, 2023 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-37833390
13.
Synthesis of novel entecavir analogues having 4'-cyano-6''-fluoromethylenecyclopentene skeletons as an aglycone moiety as highly potent and long-acting anti-hepatitis B virus agent.
RSC Adv
; 13(23): 15999-16011, 2023 May 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37265996
14.
Structure-Activity Relationship Studies of SARS-CoV-2 Main Protease Inhibitors Containing 4-Fluorobenzothiazole-2-carbonyl Moieties.
J Med Chem
; 66(19): 13516-13529, 2023 Oct 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37756225
15.
GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.
Sci Adv
; 9(28): eadg2955, 2023 07 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37436982
16.
Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Nat Commun
; 14(1): 1076, 2023 02 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-36841831
17.
Generation of Angiotensin-Converting Enzyme 2/Transmembrane Protease Serine 2-Double-Positive Human Induced Pluripotent Stem Cell-Derived Spheroids for Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Drug Evaluation.
Microbiol Spectr
; 10(6): e0349022, 2022 12 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36314907
18.
Droplet digital PCR assay provides intrahepatic HBV cccDNA quantification tool for clinical application.
Sci Rep
; 12(1): 2133, 2022 02 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35136096
19.
Design, Synthesis and X-Ray Structural Studies of Potent HIV-1 Protease Inhibitors Containing C-4 Substituted Tricyclic Hexahydro-Furofuran Derivatives as P2 Ligands.
ChemMedChem
; 17(9): e202200058, 2022 05 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35170223
20.
Potent and biostable inhibitors of the main protease of SARS-CoV-2.
iScience
; 25(11): 105365, 2022 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36338434