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1.
Evaluation of Drug-Drug Interactions via Inhibition of Hydrolases by Orlistat, an Anti-Obesity Drug.
Drug Metab Dispos
; 51(8): 1016-1023, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37137721
2.
Quantitative Analysis of mRNA and Protein Expression Levels of Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoforms in the Human Intestine.
Drug Metab Dispos
; 51(12): 1569-1577, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37722844
3.
Development and Validation of a Proteomic Correlation Profiling Technique to Detect and Identify Enzymes Involved in Metabolism of Drugs of Concern.
Drug Metab Dispos
; 51(7): 824-832, 2023 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-37156625
4.
Methionine Sulfoxide Reductase A in Human and Mouse Tissues is Responsible for Sulindac Activation, Making a Larger Contribution than the Gut Microbiota.
Drug Metab Dispos
; 50(5): 725-733, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35279645
5.
Role of Human Arylacetamide Deacetylase (AADAC) on Hydrolysis of Eslicarbazepine Acetate and Effects of AADAC Genetic Polymorphisms on Hydrolase Activity.
Drug Metab Dispos
; 49(4): 322-329, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33446525
6.
Differences in Hydrolase Activities in the Liver and Small Intestine between Marmosets and Humans.
Drug Metab Dispos
; 49(9): 718-728, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34135089
7.
Arylacetamide deacetylase knockout mice are sensitive to ketoconazole-induced hepatotoxicity and adrenal insufficiency.
Biochem Pharmacol
; 195: 114842, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34798123
8.
Arylacetamide deacetylase as a determinant of the hydrolysis and activation of abiraterone acetate in mice and humans.
Life Sci
; 284: 119896, 2021 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34450168
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