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1.
Predicting the in vivo developmental toxicity of fenarimol from in vitro toxicity data using PBTK modelling-facilitated reverse dosimetry approach.
Toxicol Appl Pharmacol
; 484: 116879, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38431230
2.
Significance of Basal Membrane Permeability of Epithelial Cells in Predicting Intestinal Drug Absorption.
Drug Metab Dispos
; 51(3): 318-328, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36810197
3.
Effects of ceramide kinase knockout on lipopolysaccharide-treated sepsis-model mice: Changes in serum cytokine/chemokine levels and increased lethality.
J Pharmacol Sci
; 150(1): 1-8, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-35926944
4.
A New Intestinal Model for Analysis of Drug Absorption and Interactions Considering Physiological Translocation of Contents.
Drug Metab Dispos
; 49(7): 581-591, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33962977
5.
Metabolome Shift in Both Metastatic Breast Cancer Cells and Astrocytes Which May Contribute to the Tumor Microenvironment.
Int J Mol Sci
; 22(14)2021 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34299050
6.
Effects on Metabolism in Astrocytes Caused by cGAMP, Which Imitates the Initial Stage of Brain Metastasis.
Int J Mol Sci
; 22(16)2021 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-34445736
7.
Implementing PRED Subroutine of NONMEM for Versatile Pharmacokinetic Analysis Using Fast Inversion of Laplace Transform (FILT).
Chem Pharm Bull (Tokyo)
; 68(9): 891-894, 2020 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32611991
8.
A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain.
J Pharmacol Sci
; 140(1): 109-112, 2019 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-31155393
9.
Physiologically Based Pharmacokinetic Modeling of Bosentan Identifies the Saturable Hepatic Uptake As a Major Contributor to Its Nonlinear Pharmacokinetics.
Drug Metab Dispos
; 46(5): 740-748, 2018 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-29475833
10.
Investigation of Metabolomic Changes in Sunitinib-Resistant Human Renal Carcinoma 786-O Cells by Capillary Electrophoresis-Time of Flight Mass Spectrometry.
Biol Pharm Bull
; 41(4): 619-627, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29607935
11.
Connexin 43 enhances Bax activation via JNK activation in sunitinib-induced apoptosis in mesothelioma cells.
J Pharmacol Sci
; 134(2): 101-107, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28602541
12.
Assessment of Drug-Drug Interaction between Warfarin and Aprepitant and Its Effects on PT-INR of Patients Receiving Anticancer Chemotherapy.
Biol Pharm Bull
; 39(5): 863-8, 2016 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26948084
13.
A new physiologically based pharmacokinetic model for the prediction of gastrointestinal drug absorption: translocation model.
Drug Metab Dispos
; 43(4): 590-602, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25616403
14.
Analysis of the disposition of a novel p38 MAPK inhibitor, AKP-001, and its metabolites in rats with a simple physiologically based pharmacokinetic model.
Drug Metab Dispos
; 43(2): 217-26, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25422274
15.
Prediction of Drug Transfer into Milk Considering Breast Cancer Resistance Protein (BCRP)-Mediated Transport.
Pharm Res
; 32(8): 2527-37, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25690342
16.
Assessment of intestinal availability (FG) of substrate drugs of cytochrome p450s by analyzing changes in pharmacokinetic properties caused by drug-drug interactions.
Drug Metab Dispos
; 42(10): 1640-5, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25061161
17.
Data-driven disease progression model of Parkinson's disease and effect of sex and genetic variants.
CPT Pharmacometrics Syst Pharmacol
; 13(4): 649-659, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38369942
18.
Disease progression modeling with temporal realignment: An emerging approach to deepen knowledge on chronic diseases.
Pharmacol Ther
; 259: 108655, 2024 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-38710372
19.
Exercise training outcomes in patients with chronic heart failure with reduced ejection fraction depend on patient background.
Front Cardiovasc Med
; 11: 1330235, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38361589
20.
High plasma linezolid concentration and impaired renal function affect development of linezolid-induced thrombocytopenia.
J Antimicrob Chemother
; 68(9): 2128-33, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23625638