Detalles de la búsqueda
1.
Reduction of brain kynurenic acid improves cognitive function.
J Neurosci
; 34(32): 10592-602, 2014 Aug 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-25100593
2.
Positive allosteric modulation of AMPA receptors from efficacy to toxicity: the interspecies exposure-response continuum of the novel potentiator PF-4778574.
J Pharmacol Exp Ther
; 347(1): 212-24, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23899905
3.
Phosphodiesterase 9A regulates central cGMP and modulates responses to cholinergic and monoaminergic perturbation in vivo.
J Pharmacol Exp Ther
; 341(2): 396-409, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22328573
4.
Delta oscillation and short-term plasticity in the rat medial prefrontal cortex: modelling NMDA hypofunction of schizophrenia.
Int J Neuropsychopharmacol
; 14(1): 29-42, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-20334724
5.
Characterization of PF-6142, a Novel, Non-Catecholamine Dopamine Receptor D1 Agonist, in Murine and Nonhuman Primate Models of Dopaminergic Activation.
Front Pharmacol
; 11: 1005, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32733245
6.
Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity.
Bioorg Med Chem Lett
; 18(12): 3611-5, 2008 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18490160
7.
Cannabinoid receptor-mediated disruption of sensory gating and neural oscillations: A translational study in rats and humans.
Neuropharmacology
; 135: 412-423, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29604295
8.
Pharmacological and computational analysis of alpha-subunit preferential GABA(A) positive allosteric modulators on the rat septo-hippocampal activity.
Neuropharmacology
; 52(3): 733-43, 2007 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-17113111
9.
Discovery of N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an agonist of the alpha7 nicotinic acetylcholine receptor, for the potential treatment of cognitive deficits in schizophrenia: synthesis and structure--activity relationship.
J Med Chem
; 49(14): 4425-36, 2006 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-16821801
10.
Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.
J Med Chem
; 48(4): 905-8, 2005 Feb 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15715459
11.
The discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242).
J Med Chem
; 58(10): 4291-308, 2015 May 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-25905800
12.
Auditory sensory gating in hippocampus and reticular thalamic neurons in anesthetized rats.
Biol Psychiatry
; 53(3): 244-53, 2003 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12559658
13.
Norepinephrine but not serotonin reuptake inhibitors enhance theta and gamma activity of the septo-hippocampal system.
Neuropsychopharmacology
; 28(5): 857-64, 2003 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-12637957
14.
Discovery and characterization of a novel dihydroisoxazole class of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiators.
J Med Chem
; 56(22): 9180-91, 2013 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24215237
15.
Role of Thalamic Projection in NMDA Receptor-Induced Disruption of Cortical Slow Oscillation and Short-Term Plasticity.
Front Psychiatry
; 2: 14, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21556284
16.
Discovery of 4-(5-methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a novel alpha 7 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders in schizophrenia: synthesis, SAR development, and in vivo efficacy in cognition models.
J Med Chem
; 53(3): 1222-37, 2010 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-20043678
17.
Preclinical pharmacology of the alpha4beta2 nAChR partial agonist varenicline related to effects on reward, mood and cognition.
Biochem Pharmacol
; 78(7): 813-24, 2009 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19501054
18.
Activation of cannabinoid-1 receptors disrupts sensory gating and neuronal oscillation: relevance to schizophrenia.
Biol Psychiatry
; 63(11): 1075-83, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18261715
19.
Design, synthesis, structure-activity relationship, and in vivo activity of azabicyclic aryl amides as alpha7 nicotinic acetylcholine receptor agonists.
Bioorg Med Chem
; 14(24): 8219-48, 2006 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-17011782
20.
Regulation of septo-hippocampal activity by 5-hydroxytryptamine(2C) receptors.
J Pharmacol Exp Ther
; 306(2): 605-15, 2003 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12734389
Resultados
1 -
20
de 20
1
Próxima >
>>